Purpose The increased incidence of colorectal cancer (CRC) has necessitated the
development of novel prognostic and predictive factors from which new diagnostic tests …

Simple Summary Kirsten rat sarcoma viral oncogene homolog (KRAS)-mutated colorectal
cancer (CRC) seems to have a different biological behavior and therapeutic approach …

Background: The clinical significance of KRAS exon 3/4 mutations in colorectal cancer
(CRC) remains unclear. We aimed to assess the prognostic value of KRAS exons 3 and 4 …

Purpose A systematic literature review was conducted to estimate the global prevalence of
Kirsten rat sarcoma virus gene (KRAS) mutations, with an emphasis on the clinically …

Background: The KRAS mutations are high-frequency somatic mutations found in colorectal
cancer patients from Western and Asian countries however, with the exception of exon 2 of …

Background: Activating mutations in KRAS have been suggested as potential predictive and
prognostic biomarkers. However, the prognostic impact of specific point mutations remains …

KRAS mutations serve a function in tumorigenesis of colorectal cancer (CRC) and guide the
use of targeted drugs. However, the prognostic value of KRAS mutations and their subtypes …

The mutation of Kirsten rat sarcoma viral oncogene homolog (KRAS) has been reported to
be prognostically important in patients with colorectal cancer (CRC). In this study, we …

Our aim was to evaluate the KRAS genotypes of Japanese colorectal cancer (CRC) patients
and to assess the effect of these genotypes on clinical outcome. A total of 99 patients with …

Background/Aim: The clinical significance of many RAS-family mutations in colorectal
cancer (CRC) remains unclear. The purpose of this study was to investigate the relationship …