Glycolytic control mechanisms: II. Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart

JR Williamson - Journal of Biological Chemistry, 1966 - ASBMB
The tissue levels of the glycolytic intermediates and adenine nucleotides were measured in
perfused rat hearts supplied with 20 mm glucose during the transition from aerobiosis to …

[引用][C] Glycolytic Control Mechanisms: I. Inhibition of glycolysis by acetate and pyruvate in the isolated, perfused rat heart

JR Williamson - Journal of Biological Chemistry, 1965 - Elsevier
Earlier studies with the perfused rat heart have shown that the rate of glycolysis was
inhibited by the addition of fatt) y acids or ketone bodies to the perfusion medium (l-4). The …

Effects of increased heart work on glycolysis and adenine nucleotides in the perfused heart of normal and diabetic rats

LH Opie, KRL Mansford, P Owen - Biochemical Journal, 1971 - portlandpress.com
1. In the isolated perfused rat heart, the contractile activity and the oxygen uptake were
varied by altering the aortic perfusion pressure, or by the atrial perfusion technique ('working …

The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart

JR Neely, RM Denton, PJ England… - Biochemical …, 1972 - portlandpress.com
1. The work of the perfused rat heart was acutely increased by raising the aortic pressure in
the Langendorff preparation from 50 to 120mmHg; within 1 min in perfusions with media …

Regulation of glycolysis in the ischemic and the anoxic myocardium

W Kübler, PG Spieckermann - Journal of Molecular and Cellular Cardiology, 1970 - Elsevier
Experiments were done in dogs with various durations of myocardial anoxia in the following
conditions:(1) so-called ischemic cardiac arrest in normo-or hypothermia;(2) anoxic …

Regulation of glycogenolysis in hearts: effects of pressure development, glucose, and FFA

Neely JR, CF Whitfield… - American Journal of …, 1970 - journals.physiology.org
NEELY, JR, CF WHITFIELD, AND HE MORGAN. Regulation of glycogenolysis in hearts:
effects of pressure development, glucose, and FFA. Am. J. Physiol. 219 (4): 1083-1088 …

[引用][C] Regulation of glycogenolysis in muscle: II. Control of glycogen phosphorylase reaction in isolated perfused heart

HE Morgan, A Parmeggiani - Journal of Biological Chemistry, 1964 - Elsevier
12 14 16 12 14 16 MINUTES MINUTES FIG. 1. Effect of glucagon and anoxia on glycogen
content, lactate production, and phosphorylase activity of the perfused heart. Hearts were …

Contribution of tissue acidosis to ischemic injury in the perfused rat heart.

JR Williamson, SW Schaffer, C Ford, B Safer - Circulation, 1976 - europepmc.org
The isolated perfused working rat heart preparation has been used to study the effects of
respiratory acidosis on myocardial metabolism and contractilly. Hearts were perfused with 5 …

The significance of phosphofructokinase to the regulation of carbohydrate metabolism

E Hofmann - … , Biochemistry and Pharmacology, Volume 75: Volume …, 2005 - Springer
A possible rate-limiting role of phosphofructokinase in muscle glycolysis was first suggested
by CogI (1942), when he interpreted observations, as showing administration of epinephrine …

Role of fructose 2, 6-bisphosphate in the control of heart glycolysis

C Depre, MH Rider, K Veitch, L Hue - Journal of Biological Chemistry, 1993 - ASBMB
The aim of this work was to study whether changes in fructose 2, 6-bisphosphate
concentration are correlated with variations of the glycolytic flux in the isolated working rat …