The relationship of genetic risk score with cardiometabolic risk factors: a cross-sectional study
Background & aims For more than eight decades, cardiovascular disease (CVD) has
remained the leading cause of death in the world. CVD risk factors are multifaceted, with …
remained the leading cause of death in the world. CVD risk factors are multifaceted, with …
Interaction between the genetic risk score and dietary protein intake on cardiometabolic traits in Southeast Asian
Background Cardiometabolic diseases are complex traits which are influenced by several
single nucleotide polymorphisms (SNPs). Thus, analysing the combined effects of multiple …
single nucleotide polymorphisms (SNPs). Thus, analysing the combined effects of multiple …
Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history
H Tada, O Melander, JZ Louie, JJ Catanese… - European heart …, 2016 - academic.oup.com
Abstract Aims Genetic risk scores (GRSs) have been associated with coronary heart disease
(CHD) in large studies. We asked whether expanding an established 27-variant GRS …
(CHD) in large studies. We asked whether expanding an established 27-variant GRS …
cardiovascular risk factors and ischemic heart disease: is the confluence of risk factors greater than the parts? A genetic approach
R Elosua, C Lluís-Ganella, I Subirana… - Circulation …, 2016 - Am Heart Assoc
Background—Cardiovascular risk factors tend to aggregate. The biological and predictive
value of this aggregation is questioned and genetics could shed light on this debate. Our …
value of this aggregation is questioned and genetics could shed light on this debate. Our …
Additive influence of genetic predisposition and conventional risk factors in the incidence of coronary heart disease: a population-based study in Greece
Objectives An additive genetic risk score (GRS) for coronary heart disease (CHD) has
previously been associated with incident CHD in the population-based Greek European …
previously been associated with incident CHD in the population-based Greek European …
Interactions of lipid genetic risk scores with estimates of metabolic health in a Danish population
JM Justesen, KH Allin, CH Sandholt… - Circulation …, 2015 - Am Heart Assoc
Background—There are several well-established lifestyle factors influencing dyslipidemia
and currently; 157 genetic susceptibility loci have been reported to be associated with serum …
and currently; 157 genetic susceptibility loci have been reported to be associated with serum …
Genetic risk scores for cardiometabolic traits in sub-Saharan African populations
K Ekoru, AA Adeyemo, G Chen… - International Journal …, 2021 - academic.oup.com
Background There is growing support for the use of genetic risk scores (GRS) in routine
clinical settings. Due to the limited diversity of current genomic discovery samples, there are …
clinical settings. Due to the limited diversity of current genomic discovery samples, there are …
Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank
R Huang, X Kong, R Geng, J Wu, T Chen, J Li, C Li… - BMC Public Health, 2024 - Springer
Background Both body mass index (BMI) and genetic factors independently contribute to
cardiovascular disease (CVD). However, it is unclear whether genetic risk modifies the …
cardiovascular disease (CVD). However, it is unclear whether genetic risk modifies the …
Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus
Objective—To investigate the associations between obesity-predisposing genetic variants,
cardiovascular biomarkers, and cardiovascular disease (CVD) risk in women with …
cardiovascular biomarkers, and cardiovascular disease (CVD) risk in women with …
[HTML][HTML] Genetic risk score for prediction of coronary heart disease in the Korean genome and Epidemiology study
H Yun, JE Lim, EY Lee - Reviews in Cardiovascular Medicine, 2023 - imrpress.com
Background: Using a genetic risk score (GRS) to predict coronary heart disease (CHD) may
detect disease earlier. The current study aims to assess whether GRS is associated with …
detect disease earlier. The current study aims to assess whether GRS is associated with …