Oligodeoxynucleotides bearing 5′-appendages consisting of a nucleobase and an amide
linkage were prepared from 5′-amino-5′-deoxyoligonucleotides, amino acid building …

Modified Oligonucleotides. Effect of 4 vs 5-atom Chimeric Internucleoside Linkages on Duplex
Stability. Gilbert Stork* a, Chengz Page 1 Pergamon 0040-4039(95)01320-2 Tetrahedron …

In an effort to discover novel oligonucleotide modifications for antisense therapeutics, we
have prepared oligodeoxyribonucleotides containing more than 200 different modifications …

A single deoxycytidine residing in an oligodeoxyribonucleotide which also contains 5-
methyldeoxycytidines can be selectively derivatized with various alkylamines by sodium …

We report here the synthesis and binding studies of oligo-2 '-deoxyribonucleotides (ODNs)
containing 2 '-deoxyuridines, modified at the 5-position by linkers ending with either one or …

N4 aralkyl-substituted cytosine nucleosides, available dxectly by displacement of the PfpO
group at C4 of 5′-O-DMT-protected nucleoside 4, were efficiently incorporated into short …

A series of oligonucleotides containing (5′ S)‐5′‐C‐butyl‐and (5′ S)‐5′‐C‐isopentyl‐
substituted 2′‐deoxyribonucleosides were designed, prepared, and characterized with the …

The synthesis of 3 '-3 '-linked oligodeoxynucleotides (ODNs) with the anthraquinonyl group
at the junction point is described. The ODNs were synthesized on a DNA synthesizer using a …

The possibility is discussed of stabilizing a DNA triple helix by covalent conjugation to the
third strand (through its terminal phosphate) of ligands that have affinity to double and triple …

A versatile, general way is described for the introduction of different functional groups into
oligonucleotides by means of a simple linker at the 2'-position of the sugar. Nucleotide …