A cure for Crohn's disease (CD), a chronic inflammatory disease of the gastrointestinal tract
of unknown etiology, is not available, so patients require lifelong management to keep …

Introduction of biological agents for the treatment of Crohn's disease (CD) has led to a
transformation of the treatment paradigm. Several biological compounds have been …

Objective To study the comparative efficacy of biologic therapy in the management of
biologic-naïve patients with Crohn disease (CD). Patients and Methods We conducted a …

Introduction The therapeutic armamentarium for managing Crohn's disease (CD) has
expanded significantly in recent decades. Several biologics with three different mechanisms …

Introduction tions, again common to both CD and UC, may include fatigue, anemia and
hypercoagulability. Unlike UC, in which the intestinal inflammation is usually continuous and …

Crohn's disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal
tract with no known cure. The inflammation that drives the disease can lead to debilitating …

Abstract Background/Aims: For many therapeutic decisions in Crohn's disease (CD), high-
grade evidence is lacking. To assist clinical decision-making, explicit panel-based …

Biological drugs have opened new therapeutic horizons for treating Crohn's disease (CD),
but have also brought with them issues related to immunogenicity, long‐term efficacy, safety …

2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

Background and aims: Data on the optimal use of conventional therapies in Crohn's disease
are lacking in guidelines. An educational programme was established to explore questions …