With widespread treatment of Helicobacter pylori infection, and that peptic ulcer diseases
are no longer considered a chronic illness and are declining in most parts of the world …

CONTEXT: Esophageal pH monitoring is considered to be the gold standard for the
diagnosis of gastroesophageal acid reflux. However, this method is very troublesome and …

Esophageal ambulatory pH impedance monitoring showed much promise in the new
millennium as a novel approach to quantifying reflux events irrespective of pH or …

Classic techniques like videofluoroscopy, stationary manometry, and ambulatory 24 h pH-
metry are routinely used in the clinic to study patients with dysphagia, chest pain and reflux …

Ambulatory esophageal pH monitoring is an essential method in patients exhibiting signs of
non-erosive reflux disease (NERD) to make an objective diagnosis. Intra-esophageal pH …

Gastroesophageal reflux disease (GERD) contributes substantially to morbidity and to costs
in the United States health care system. The burden of this disease has resulted in attempts …

Gastroesophageal reflux disease (GERD) is a disease predominantly seen in the West but
there is a rising trend in Asia. Ambulatory 24-hour catheter-based pH monitoring has been …

1. Demonstrate an understanding of the natural history and manifestations of reflux disease
2. Evaluate the role of diagnostic testing such as endoscopy, esophageal manometry …

Until recently catheter-based 24-h pH monitoring has been the primary methodology for the
objective diagnosis of gastroesophageal reflux disease. Yet, this system has some …

Background & Aims Current diagnostic tests for gastroesophageal reflux disease (GERD)
are suboptimal and do not accurately and reliably measure chronicity of reflux. A minimally …