An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

M Simren, H Abrahamsson, ES Björnsson - Gut, 2001 - gut.bmj.com
BACKGROUND/AIMS Visceral hypersensitivity is a feature of the irritable bowel syndrome
(IBS). Postprandial symptoms are common in these patients. The effects of nutrients on …

Nutrient‐dependent enhancement of rectal sensitivity in irritable bowel syndrome (IBS)

M Simrén, P Agerforz, ES Björnsson… - …, 2007 - Wiley Online Library
Food‐related gastrointestinal symptoms are common in irritable bowel syndrome (IBS), but
the mechanisms behind this are unclear. Enhanced colorectal sensitivity after duodenal lipid …

Visceral sensitivity and symptoms in patients with constipation-or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion

MP Caldarella, A Milano, F Laterza… - Official journal of the …, 2005 - journals.lww.com
BACKGROUND Visceral hypersensitivity is common in Irritable Bowel Syndrome (IBS)
patients, and symptoms exacerbate postprandially. Yet the effects of nutrients on visceral …

Lipid-induced colonic hypersensitivity in the irritable bowel syndrome: the role of bowel habit, sex, and psychologic factors

M Simrén, H Abrahamsson, ES Björnsson - Clinical Gastroenterology and …, 2007 - Elsevier
Background & Aims: Duodenal lipid infusion increases colonic hypersensitivity in irritable
bowel syndrome (IBS). Whether this is affected by bowel habit, psychologic factors, or sex is …

Altered rectal perception is a biological marker of patients with irritable bowel syndrome

H Mertz, B Naliboff, J Munakata, N Niazi, EA Mayer - Gastroenterology, 1995 - Elsevier
Background & Aims: Lowered visceral perception thresholds have been suggested as a
biological marker of irritable bowel syndrome (IBS). The current study sought to determine …

Altered rectal perception in irritable bowel syndrome is associated with symptom severity

I Posserud, A Syrous, L Lindström, J Tack… - Gastroenterology, 2007 - Elsevier
Background & Aims: Diverging results exist regarding the connection between altered
visceral perception and gastrointestinal (GI) symptoms, as well as the effects of …

Visceral hypersensitivity following cold water intake in subjects with irritable bowel syndrome

XL Zuo, YQ Li, L Shi, GP Lv, RG Kuang, XF Lu… - Journal of …, 2006 - Springer
Background Visceral hypersensitivity has been shown to be present in irritable bowel
syndrome (IBS). This study sought to investigate rectal sensitivity and abdominal symptoms …

Evidence for two distinct perceptual alterations in irritable bowel syndrome

BD Naliboff, J Munakata, S Fullerton, RH Gracely… - Gut, 1997 - gut.bmj.com
Background and aims—Visceral hyperalgesia has been implicated as a factor contributing
to symptom generation in irritable bowel syndrome (IBS). However, previous studies using …

Symptoms and visceral perception in patients with pain-predominant irritable bowel syndrome

T Lembo, B Naliboff, J Munakata… - Official journal of the …, 1999 - journals.lww.com
Objective: Abdominal pain is thought to be a hallmark of the irritable bowel syndrome (IBS),
although currently used symptom criteria do not differentiate between abdominal pain and …

Heightened visceral sensation in functional gastrointestinal disease is not site-specific: evidence for a generalized disorder of gut sensitivity

KC Trimble, R Farouk, A Pryde, S Douglas… - Digestive diseases and …, 1995 - Springer
Alteration in visceral sensation locally at the site of presumed symptom origin in the
gastrointestinal tract has been proposed as an important etiopathological mechanism in the …