Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy

EW Lothman, DA Rempe… - Journal of …, 1995 - journals.physiology.org
1. In this report we compare changes of excitatory neurotransmission within the CA1 region
and the dentate gyrus (DG) in a model of chronic temporal lobe epilepsy (TLE). Extracellular …

Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy

PS Mangan, DA Rempe… - Journal of …, 1995 - journals.physiology.org
1. In this report we compare changes in inhibitory neurotransmission within the CA1 region
and the dentate gyrus (DG) in a model of chronic temporal lobe epilepsy (TLE). Extracellular …

Regional heterogeneity of pathophysiological alterations in CA1 and dentate gyrus in a chronic model of temporal lobe epilepsy

DA Rempe, PS Mangan… - Journal of …, 1995 - journals.physiology.org
1. Extracellular and intracellular recording techniques were employed in brain slice
preparations to characterize responses of hippocampal tissue in the post-self sustaining …

Ontogeny of altered synaptic function in a rat model of chronic temporal lobe epilepsy

PS Mangan, EH Bertram III - Brain research, 1998 - Elsevier
In the limbic status model of chronic temporal lobe epilepsy, hippocampal stimulation
induces acute status epilepticus in rats; recurrent, spontaneous seizures develop following …

Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: a model of status epilepticus

A Rafiq, YF Zhang, RJ DeLorenzo… - Journal of …, 1995 - journals.physiology.org
1. Combined hippocampal-parahippocampal slices were employed to study the
development of complex epileptiform discharges after Schaeffer collateral stimulation in …

Long‐lasting increased excitability differs in dentate gyrus vs. CA1 in freely moving chronic epileptic rats after electrically induced status epilepticus

JA Gorter, EA van Vliet, E Aronica… - …, 2002 - Wiley Online Library
A paired‐pulse (PP) stimulation protocol was used to examine changes in field potentials
(fEPSPs), locally evoked in CA1 via Schaffer/commissural fiber stimulation and in the …

The dentate gyrus as a regulated gate for the propagation of epileptiform activity.

U Heinemann, H Beck, JP Dreier, E Ficker… - Epilepsy research …, 1992 - europepmc.org
Properties of the interaction between the entorhinal cortex (EC) and the dentate gyrus were
studied in a combined EC hippocampal slice preparation in which most of the fiber …

Long-term change in synaptic transmission in CA3 circuits followed by spontaneous rhythmic activity in rat hippocampal slices

K Nakashima, H Hayashi, O Shimizu, S Ishizuka - Neuroscience Research, 2001 - Elsevier
The relevance of long-term potentiation (LTP) at excitatory synapses in CA3 circuits to
generation of spontaneous epileptiform bursts in CA3 was investigated using rat …

Low-calcium epileptiform activity in the hippocampus in vivo

Z Feng, DM Durand - Journal of neurophysiology, 2003 - journals.physiology.org
It has been clearly established that nonsynaptic interactions are sufficient for generating
epileptiform activity in brain slices. However, it is not known whether this type of epilepsy …

Interneurons in area CA1 stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic input in chronically epileptic animals

DA Rempe, EH Bertram… - Journal of …, 1997 - journals.physiology.org
Rempe, DA, EH Bertram, JM Williamson, and EW Lothman. Interneurons in area CA1
stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic …