The lymphatic network of mammalian heart is an important regulator of interstitial fluid
compartment and immune cell trafficking. We observed a remodeling of the cardiac …

Background Lymphatic vessels interconnect with blood vessels to form an elaborate system
that aids in the control of tissue pressure and edema formation. Although the lymphatic …

Background—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic
malfunction causes edema. The heart has an extensive lymphatic network displaying a …

Aims Lymphatics are essential for cardiac health, and insufficient lymphatic expansion
(lymphangiogenesis) contributes to development of heart failure (HF) after myocardial …

Cardiac lymphangiogenesis plays an important physiological role in the regulation of
interstitial fluid homeostasis, inflammatory, and immune responses. Impaired or excessive …

The lymphatic vasculature, which accompanies the blood vasculature in most organs, is
indispensable in the maintenance of tissue fluid homeostasis, immune cell trafficking, and …

Recent advances in our understanding of the lymphatic system, its function, development,
and role in pathophysiology have changed our views on its importance. Historically thought …

The lymphatic system plays crucial roles in regulating fluid homeostasis, immune
surveillance, and lipid transport. As is in most of the body's organs, the heart possesses an …

Myocardial infarction (MI) arising from obstruction of the coronary circulation engenders
massive cardiomyocyte loss and replacement by non-contractile scar tissue, leading to …

The lymphatic vasculature has an essential role in maintaining normal fluid balance in
tissues and modulating the inflammatory response to injury or pathogens. Disruption of …