Aberrant hippocampal neurogenesis contributes to learning and memory deficits in a mouse model of repetitive mild traumatic brain injury
K Greer - 2019 - vtechworks.lib.vt.edu
Adult hippocampal neurogenesis, or the process of creating new neurons in the dentate
gyrus (DG) of the hippocampus, underlies learning and memory capacity. This cognitive …
gyrus (DG) of the hippocampus, underlies learning and memory capacity. This cognitive …
[PDF][PDF] Activation of Early Neural Progenitors Is Required for Traumatic Brain Injury-Induced Hippocampal Neurogenesis
TS Yu - 2008 - utswmed-ir.tdl.org
Traumatic brain injury (TBI) is the most common form of acquired brain injury in both children
and adults in the United States. TBI causes neuronal loss and results in a variety of …
and adults in the United States. TBI causes neuronal loss and results in a variety of …
[HTML][HTML] Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments
K Greer, EKG Basso, C Kelly, A Cash, E Kowalski… - Scientific Reports, 2020 - nature.com
Brain injury resulting from repeated mild traumatic insult is associated with cognitive
dysfunction and other chronic co-morbidities. The current study tested the effects of aberrant …
dysfunction and other chronic co-morbidities. The current study tested the effects of aberrant …
The absence of a neurogenic response to a repeated concussive-like injury in mice
A Weingarten, TM Madjou, SN Yeturu, N Samudrala… - bioRxiv, 2023 - biorxiv.org
In response to traumatic brain injury (TBI), the brain increases its generation of new neurons
(neurogenesis) within the hippocampus, a brain region critical for learning and memory …
(neurogenesis) within the hippocampus, a brain region critical for learning and memory …
[HTML][HTML] Mild traumatic brain injury induces transient, sequential increases in proliferation, neuroblasts/immature neurons, and cell survival: a time course study in the …
LR Clark, S Yun, NK Acquah, PL Kumar… - Frontiers in …, 2021 - frontiersin.org
Mild traumatic brain injuries (mTBIs) are prevalent worldwide. mTBIs can impair
hippocampal-based functions such as memory and cause network hyperexcitability of the …
hippocampal-based functions such as memory and cause network hyperexcitability of the …
Functional integration of adult-born hippocampal neurons after traumatic brain injury
LE Villasana, KN Kim, GL Westbrook, E Schnell - eneuro, 2015 - eneuro.org
Traumatic brain injury (TBI) increases hippocampal neurogenesis, which may contribute to
cognitive recovery after injury. However, it is unknown whether TBI-induced adult-born …
cognitive recovery after injury. However, it is unknown whether TBI-induced adult-born …
Traumatic brain injury and hippocampal neurogenesis: Functional implications
In the adult brain, self-renewing radial-glia like (RGL) progenitor cells have been shown to
reside in the subventricular zone and the subgranular zone of the hippocampus. A large …
reside in the subventricular zone and the subgranular zone of the hippocampus. A large …
Neurologic impairment following closed head injury predicts post-traumatic neurogenesis
LE Villasana, GL Westbrook, E Schnell - Experimental neurology, 2014 - Elsevier
In the mammalian hippocampus, neurogenesis persists into adulthood, and increased
generation of newborn neurons could be of clinical benefit following concussive head …
generation of newborn neurons could be of clinical benefit following concussive head …
Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury
Significant spontaneous recovery occurs after essentially all forms of serious brain injury,
although the mechanisms underlying this recovery are unknown. Given that many forms of …
although the mechanisms underlying this recovery are unknown. Given that many forms of …
Temporal Analysis of Neurogenesis and Microglia Changes after Mild Traumatic Brain Injury in the Adult Male C57BL/6J Mouse
LR Clark - 2021 - search.proquest.com
Traumatic brain injury (TBI) affects millions of people every year. Injuries can have a range
of severities from mild to severe, but all injuries have the potential to result in lasting …
of severities from mild to severe, but all injuries have the potential to result in lasting …