Current techniques to evaluate the efficacy of potential treatments for airways diseases in
preclinical models are generally invasive and terminal. In the past few years, the flexibility of …

Magnetic resonance imaging (MRI) can be used in pre-clinical studies as a non-invasive
imaging tool for assessing the morphological and functional impact of lung diseases and for …

Over the past several years, magnetic resonance imaging (MRI) has become an established
tool in the drug discovery and development process. The main advantages of MRI are its …

Magnetic resonance imaging (MRI) of the lung has shown tremendous progress in recent
years. This includes parallel imaging, new contrast agents and mechanisms, ultrafast …

Lung imaging has traditionally relied on x‐ray methods, since proton MRI is limited to some
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …

Understanding how the mammalian respiratory system works and how it changes in disease
states and under the influence of drugs is frequently pursued in model systems such as …

Hyperpolarized (HP) gases are a new class of contrast agents that permit to obtain high
temporal and spatial resolution magnetic resonance images (MRIs) of the lung airspaces …

The need for airway imaging is defined by the limited sensitivity of common clinical tests like
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …

Proton signals from lung parenchyma were detected with the use of a gradient‐echo
sequence to noninvasively obtain information on pulmonary function in models of airway …

Ultrashort echo time (550 μs) MR imaging was implemented to track the emphysema
development in mice lung challenged with elastase. Two parameters, namely, signal …