We now recognise that withdrawal symptoms from antidepressants are common, and can be
severe and long-lasting in some people. Many withdrawal symptoms overlap with symptoms …

A substantial proportion of the burden of depression arises from its recurrent nature. The risk
of relapse after antidepressant medication (ADM) discontinuation is high but not uniform …

The aim of this article is to discuss the validity of relapse prevention trials and the issue of
withdrawal confounding in these trials. Recommendations for long-term antidepressant …

Background: Relapse prevention trials build the scientific foundation for recommendation of
antidepressant continuation and maintenance therapy. However, the validity of the evidence …

Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

Background: Stopping antidepressants commonly causes withdrawal symptoms, which can
be severe and long-lasting. National Institute for Health and Care Excellence (NICE) …

Withdrawal reactions when coming off antidepressants have long been neglected or
minimised. It took almost two decades after the selective serotonin reuptake inhibitors …

Background Several long‐term double‐blind placebo controlled trials have shown
prophylactic antidepressant therapy in unipolar depression. The goal of this work was to …

We read with great interest the recent review of antidepressant withdrawal by Davies and
Read and the widespread press coverage which followed. We agree that symptoms …

Introduction The incidence and severity of withdrawal effects when coming off
antidepressants (ADs) have recently received considerable attention. National guidelines on …