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Abstract The Human Reference Atlas (HRA) aims to map all of the cells of the human body
to advance biomedical research and clinical practice. This Perspective presents …

Comprehensively characterizing the cellular composition and organization of tissues has
been a long-term scientific challenge that has limited our ability to study fundamental and …

The recent advent of methods for high-throughput single-cell molecular profiling has
catalyzed a growing sense in the scientific community that the time is ripe to complete the …

The Human Cell Atlas (HCA) will be made up of comprehensive reference maps of all
human cells-the fundamental units of life-as a basis for understanding fundamental human …

International efforts are underway to provide a comprehensive survey of cells across the
human life span (,). These efforts assign cell “types” on the basis of a set of information-rich …

Abstract The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human
Cell Atlas, aims to create a comprehensive reference map of cells during development. This …

Transformative technologies are enabling the construction of three-dimensional maps of
tissues with unprecedented spatial and molecular resolution. Over the next seven years, the …

To the Editor—Building the Human Cell Atlas (HCA) requires consistent and agile
experimental designs, standardized operating protocols (SOPs), benchmarks and quality …

Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale
spatial atlas of the healthy human body at single-cell resolution by applying advanced …