Background Identifying differences and similarities between cutaneous lymphocyte antigen
(CLA)+ polarized T-cell subsets in children versus adults with atopic dermatitis (AD) is …

Background The circulating immune phenotype was defined in adults and young children
with early atopic dermatitis (AD), but chronologic changes in the blood of infants and …

Background Past studies of blood T-cell phenotyping in patients with atopic dermatitis (AD)
have provided controversial results and were mostly performed before the identification of …

Background Atopic dermatitis (AD) affects 15% to 25% of children and 4% to 7% of adults.
Paradigm-shifting discoveries about AD have been based on adult biomarkers, reflecting …

Background Although atopic dermatitis (AD) often presents in infancy and persists into
adulthood, comparative characterization of AD skin among different pediatric age groups is …

Background Atopic dermatitis (AD) is an inflammatory skin disease whose lesions can have
two stages: acute and chronic. In skin biopsies a biphasic pattern of cytokine expression has …

Atopic dermatitis (AD) is a chronic skin disorder, characterized by infiltration of activated
memory CD4+ T cells into skin. A model to study the onset of allergic inflammation in a …

Cutaneous lymphocyte‐associated antigen (CLA+) T cells are specialized for skin homing
and represent the main T‐cell population in atopic dermatitis (AD) lesions. CLA+ is …

In allergic inflammations of the skin, activation of CD4+ T cells was demonstrated to play an
important role; however, a minor role for CD8+ T cells is implied. In the present study, we …

Background Although atopic dermatitis (AD) often starts in early childhood, detailed tissue
profiling of early-onset AD in children is lacking, hindering therapeutic development for this …