Basic mechanisms of catastrophic epilepsy–overview from animal models
AS Galanopoulou - Brain and Development, 2013 - Elsevier
Infantile spasms are age-specific seizures of infantile epileptic encephalopathies that are
usually associated with poor epilepsy and neurodevelopmental outcomes. The current …
usually associated with poor epilepsy and neurodevelopmental outcomes. The current …
Infantile spasms: a critical review of emerging animal models
CE Stafstrom - Epilepsy Currents, 2009 - journals.sagepub.com
Infantile spasms is a developmental epilepsy syndrome with unique clinical and EEG
features, a specific pattern of pharmacological responsiveness, and poor outcome in terms …
features, a specific pattern of pharmacological responsiveness, and poor outcome in terms …
Basic science behind the catastrophic epilepsies
JM Rho - Epilepsia, 2004 - Wiley Online Library
The major catastrophic epileptic syndromes of childhood include infantile spasms, Lennox‐
Gastaut syndrome, and the progressive myoclonus epilepsies (PMEs). Although each of …
Gastaut syndrome, and the progressive myoclonus epilepsies (PMEs). Although each of …
Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: a view from preclinical studies
AS Galanopoulou, SL Moshé - Neurobiology of disease, 2015 - Elsevier
Early onset and infantile epileptic encephalopathies (EIEEs) are usually associated with
medically intractable or difficult to treat epileptic seizures and prominent cognitive …
medically intractable or difficult to treat epileptic seizures and prominent cognitive …
Infantile spasms: hypothesis-driven therapy and pilot human infant experiments using corticotropin-releasing hormone receptor antagonists
TZ Baram, WG Mitchell, K Brunson… - Developmental …, 1999 - karger.com
Abstract Background and Rationale: Infantile spasms (IS) are an age-specific seizure
disorder occurring in 1: 2,000 infants and associated with mental retardation in∼ 90% of …
disorder occurring in 1: 2,000 infants and associated with mental retardation in∼ 90% of …
Infantile spasms: criteria for an animal model
CE Stafstrom, GL Holmes - International review of neurobiology, 2002 - Elsevier
Infantile spasms is an epilepsy syndrome with several distinctive features, including age
specificity during infancy, characteristic semiology (epileptic spasms), specific …
specificity during infancy, characteristic semiology (epileptic spasms), specific …
Animal models in epileptic spasms and the development of novel treatment options
KT Barrett, A Choudhary, B Charkhand… - Journal of Clinical …, 2022 - journals.lww.com
The infantile spasms (IS) syndrome is a catastrophic developmental epileptic
encephalopathy syndrome characterized by an age-specific expression of epileptic spasms …
encephalopathy syndrome characterized by an age-specific expression of epileptic spasms …
Brain maturational aspects relevant to pathophysiology of infantile spasms
G Avanzini, F Panzica, S Franceschetti - International Review of …, 2002 - Elsevier
Infantile spasms (IS) are so typically associated with West syndrome that the term IS,
properly referred to as a seizure type, is currently used synonymously with this severe …
properly referred to as a seizure type, is currently used synonymously with this severe …
Developing an animal model for infantile spasms: pathogenesis, problems and progress
ED Marsh, JA Golden - Disease Models & Mechanisms, 2009 - journals.biologists.com
Infantile spasms (IS), the most common of the early epileptic encephalopathies, afflicts
thousands of children each year and results in significant disability. Also known as West …
thousands of children each year and results in significant disability. Also known as West …
Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?
ACH Ng, A Choudhary, KT Barrett, C Gavrilovici… - …, 2024 - Wiley Online Library
The devastating developmental and epileptic encephalopathy of infantile epileptic spasms
syndrome (IESS) has numerous causes, including, but not limited to, brain injury, metabolic …
syndrome (IESS) has numerous causes, including, but not limited to, brain injury, metabolic …