Streptococcus gordonii type I lipoteichoic acid contributes to surface protein biogenesis

BP Lima, K Kho, BL Nairn, JR Davies, G Svensäter… - Msphere, 2019 - Am Soc Microbiol
Lipoteichoic acid (LTA) is an abundant polymer of the Gram-positive bacterial cell envelope
and is essential for many species. Whereas the exact function of LTA has not been …

Streptococcus pneumoniae, S. mitis, and S. oralis Produce a Phosphatidylglycerol-Dependent, ltaS-Independent Glycerophosphate-Linked Glycolipid

Y Wei, LR Joyce, AM Wall, Z Guan, KL Palmer - Msphere, 2021 - Am Soc Microbiol
Lipoteichoic acid (LTA) is a Gram-positive bacterial cell surface polymer that participates in
host-microbe interactions. It was previously reported that the major human pathogen …

Inactivation of DltA Modulates Virulence Factor Expression in Streptococcus pyogenes

KH Cox, E Ruiz-Bustos, HS Courtney, JB Dale… - PLoS …, 2009 - journals.plos.org
Background D-alanylated lipoteichoic acid is a virtually ubiquitous component of Gram-
positive cell walls. Mutations in the dltABCD operon of numerous species exhibit pleiotropic …

Synthesis of glycerol phosphate lipoteichoic acid in Staphylococcus aureus

A Gründling, O Schneewind - Proceedings of the National …, 2007 - National Acad Sciences
Lipoteichoic acid (LTA), a glycerol phosphate surface polymer, is a component of the
envelope of Gram-positive bacteria. However, the molecular basis for its synthesis or …

Pleiotropic Roles of Polyglycerolphosphate Synthase of Lipoteichoic Acid in Growth of Staphylococcus aureus Cells

Y Oku, K Kurokawa, M Matsuo, S Yamada… - Journal of …, 2009 - Am Soc Microbiol
Lipoteichoic acid (LTA) is one of two anionic polymers on the surface of the gram-positive
bacterium Staphylococcus aureus. LTA is critical for the bacterium-host cell interaction and …

lipoteichoic acids are essential for pneumococcal colonization and membrane integrity

M Brendel, TP Kohler, JV Neufend, A Puppe… - Journal of Innate …, 2024 - karger.com
Introduction: The hydrophilic, polymeric chain of the lipoteichoic acid (LTA) of the Gram-
positive pathobiont Streptococcus pneumoniae is covalently linked to the …

Relationship between Expression of the Family of M Proteins and Lipoteichoic Acid to Hydrophobicity and Biofilm Formation in Streptococcus pyogenes

HS Courtney, I Ofek, T Penfound, V Nizet, MA Pence… - PLoS …, 2009 - journals.plos.org
Background Hydrophobicity is an important attribute of bacteria that contributes to adhesion
and biofilm formation. Hydrophobicity of Streptococcus pyogenes is primarily due to …

Lipoteichoic acid synthesis and function in gram-positive bacteria

MG Percy, A Gründling - Annual review of microbiology, 2014 - annualreviews.org
Lipoteichoic acid (LTA) is an important cell wall polymer found in gram-positive bacteria.
Although the exact role of LTA is unknown, mutants display significant growth and …

Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

N Heß, F Waldow, TP Kohler, M Rohde… - Nature …, 2017 - nature.com
Teichoic acid (TA), a crucial cell wall constituent of the pathobiont Streptococcus
pneumoniae, is bound to peptidoglycan (wall teichoic acid, WTA) or to membrane …

A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity

I Fedtke, D Mader, T Kohler, H Moll… - Molecular …, 2007 - Wiley Online Library
Many Gram‐positive bacteria produce lipoteichoic acid (LTA) polymers whose physiological
roles have remained a matter of debate because of the lack of LTA‐deficient mutants. The …