The c-fos proto-oncogene has been implicated as a central regulatory component of the
nuclear response i: o mitogens and other extracellular stimuli. Embryonic stem cells targeted …

reviews Proto-oncogene los: a multifaceted gene Page 1 TIG -- Apn'! 19 Muller, A., M:~mm, T.
and Lurquin, PF (1984) B/ochem. Biophys. Res. Commun. 123, 458-462 20 McKelvie, AD (1962)Rad …

The proto-oncogene transcription factors Fos and Jun form a heterodimeric complex that
binds to DNA and regulates expression of specific target genes. Continuous expression of c …

The c‐fos proto‐oncogene is believed to play a pivotal role in transducing growth factor‐
mediated signals from the extracellular milieu into the nucleus. c‐fos protein dimerizes with c …

The expression of fos protein was examined in 30 cases of human osteosarcoma as
formalin-fixed and paraffin-embedded tissue sections using two monoclonal antibodies and …

We have generated transgenic mice expressing the proto-oncogene c-fos from an H-2Kb
class I MHC promoter as a tool to identify and isolate cell populations which are sensitive to …

1. Introduction 2. Discovery and structure of c-and v-fos genes c-fos gene is one of the most
actively studied (protoonco) genes; more than 3000 related references can be identified in a …

Publisher Summary This chapter reviews the biology and pathology of the tumors induced
by the fos gene. The chapter discusses the structure of the fos gene, and its expression in …

Fra-2, one of the Fos-related antigens, is promptly expressed after the growth stimulation of
fibroblasts, but its induction peak is later than that of c-Fos. In this report, we examined …

We demonstrate that a member of the fos family, the fos B gene, gives rise to two transcripts
by alternative splicing of exon 4, generating two proteins, FosB of 338 amino acids and a …