Article abstract In spinocerebellar ataxia type 2 (SCA-2), a difference of three CAG repeats
distinguishes normal alleles (14 to 31 repeats) from pathogenic alleles (34 to 57 repeats). All …

Abstract Spinocerebellar ataxia 2 (SCA2) is caused by the expansion of an unstable CAG
repeat encoding a polyglutamine tract. One hundred and eighty four index patients with …

Sixteen patients from nine Chinese families with spinocerebellar ataxia type 2 (SCA2) were
heterozygous for a CAG repeat expansion in the SCA2 gene containing 37 to 56 repeats …

Spinocerebellar ataxia type 6 (SCA6) is a newly classified autosomal-dominant cerebellar
ataxia (ADCA) associated with CAG repeat expansion. We screened 111 patients with …

The autosomal dominant spinocerebellar ataxias (ADSCAs) are a heterogeneous group of
late-onset neurodegenerative disorders with overlapping clinical features. Genetic linkage …

Spinocerebellar ataxia-2 (SCA2) is an autosomal dominant ataxia caused by an abnormal
CAG repeat expansion in a novel gene on chromosome 12q24. 1. The size of the mutant …

The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24. 1. A1. 1–
megabase contig in the candidate region was assembled in P1 artificial chromosome and …

Fig. 1 PCR analysis of CAG repeat at SCA7 locus. Products were electrophoresed in
denaturing 6% polyacrylamide/7 M urea gel. A: DNA analysis by radioactive PCR of the …

A Siberian kindred with spinocerebellar ataxia genetically linked to the SCA1 locus on
chromosome 6p has been screened for the CAG triplet expansion within the coding region …

Background Autosomal dominant cerebellar ataxias are a clinical and genetically
heterogeneous group of progressive neurodegenerative diseases, at present associated …