Aspirin-loaded electrospun poly (ε-caprolactone) tubular scaffolds: potential small-diameter vascular grafts for thrombosis prevention

C Del Gaudio, E Ercolani, P Galloni, F Santilli… - Journal of Materials …, 2013 - Springer
Thrombosis is the main cause of failure of small-diameter synthetic vascular grafts when
used for by-pass procedures. The development of bioresorbable vascular scaffolds with …

Preparation and in vivo evaluation of surface heparinized small diameter tissue engineered vascular scaffolds of poly (ε-caprolactone) embedded with collagen suture

X Hui, X Geng, L Jia, Z Xu, L Ye, Y Gu… - Journal of …, 2020 - journals.sagepub.com
Herein biodegradable poly (ε-caprolactone) was electrospun into tubular microfibrous
scaffolds and modified by the surface heparinization and wrapping of Type I collagen suture …

A nanofibrous bilayered scaffold for tissue engineering of small‐diameter blood vessels

AZ Kharazi, M Atari, E Vatankhah… - Polymers for …, 2018 - Wiley Online Library
The main challenge encountered in clinical efficacy of tissue engineered vascular grafts is
development of a biomimetic scaffold. To establish a scaffold resembling the architecture of …

Improvement of cell infiltration in electrospun polycaprolactone scaffolds for the construction of vascular grafts

K Wang, M Zhu, T Li, W Zheng, LL Xu… - Journal of …, 2014 - ingentaconnect.com
The less-than-ideal cell infiltration resulting from inherently small pore size limits the
application of electrospinning scaffold in tissue engineering and regeneration medicine. The …

Electrospun biodegradable elastic polyurethane scaffolds with dipyridamole release for small diameter vascular grafts

P Punnakitikashem, D Truong, JU Menon, KT Nguyen… - Acta biomaterialia, 2014 - Elsevier
Acellular biodegradable small diameter vascular grafts (SDVGs) require antithrombosis,
intimal hyperplasia inhibition and rapid endothelialization to improve the graft patency …

[HTML][HTML] Use of 3D printing for the development of biodegradable antiplatelet materials for cardiovascular applications

J Domínguez-Robles, L Diaz-Gomez, E Utomo… - Pharmaceuticals, 2021 - mdpi.com
Small-diameter synthetic vascular grafts are required for surgical bypass grafting when there
is a lack of suitable autologous vessels due to different reasons, such as previous …

Preparation of small‐diameter tissue‐engineered vascular grafts electrospun from heparin end‐capped PCL and evaluation in a rabbit carotid artery replacement …

X Jin, X Geng, L Jia, Z Xu, L Ye, Y Gu… - Macromolecular …, 2019 - Wiley Online Library
Aiming to construct small diameter (ID< 6 mm) off‐the‐shelf tissue‐engineered vascular
grafts, the end‐group heparinizd poly (ε‐caprolactone)(PCL) is synthesized by a three‐step …

Surface-modified bioresorbable electrospun scaffolds for improving hemocompatibility of vascular grafts

PC Caracciolo, MI Rial-Hermida… - Materials Science and …, 2017 - Elsevier
The replacement of small-diameter vessels is one of the main challenges in tissue
engineering. Moreover, the surface modification of small-diameter vascular grafts (SDVG) is …

Electrospun tubular scaffolds: On the effectiveness of blending poly(ε‐caprolactone) with poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate)

C Del Gaudio, L Fioravanzo, M Folin… - … Research Part B …, 2012 - Wiley Online Library
Tissue engineering can effectively contribute to the development of novel vascular
prostheses aimed to overcome the well‐known drawbacks of small‐diameter grafts. To date …

Preliminary in Vivo Evaluation of a Hybrid Armored Vascular Graft Combining Electrospinning and Additive Manufacturing Techniques: Supplementary Issue: Current …

C Spadaccio, F Nappi, F De Marco… - Drug Target …, 2016 - journals.sagepub.com
In this study, we tested in vivo effectiveness of a previously developed poly-L-lactide/poly-8-
caprolactone armored vascular graft releasing heparin. This bioprosthesis was designed in …