Aspergillus fumigatus is a saprophytic, filamentous fungus found in soils and compost and
the causative agent of several pulmonary diseases in humans, birds, and other mammals. A …

In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease
that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in …

All humans are continuously exposed to inhaled Aspergillus conidia, yet healthy hosts clear
the organism without developing disease and without the development of antibody-or cell …

▪ Abstract Infections with mold pathogens have emerged as an increasing risk faced by
patients under sustained immunosuppression. Species of the Aspergillus family account for …

Opportunistic animal and plant pathogens, well represented by the genus Aspergillus, have
evolved unique mechanisms to adapt to and avoid host defenses. Aspergillus fumigatus, an …

Aspergillus fumigatus is an important pathogen of immunocompromised hosts, causing
pneumonia and invasive disseminated disease with high mortality. The factors contributing …

Infection models are essential tools for studying microbial pathogenesis. Murine models are
considered the “gold standard” for studying in vivo infections caused by Aspergillus species …

Aspergillus fumigatus is a well adapted, opportunistic fungus that causes a severe and
commonly fatal disease, invasive pulmonary aspergillosis (IPA), in highly …

Infection by the human fungal pathogen Aspergillus fumigatus induces hypoxic
microenvironments within the lung that can alter the course of fungal pathogenesis. How …

Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …