Before the development of the inactivated poliovirus vaccine (IPV) and live oral poliovirus
vaccine (OPV), sporadic outbreaks of poliomyelitis were reported to cause as many as 18 …

Owing to the concerted efforts of countries worldwide, the incidence of paralytic poliomyelitis
due to wild poliovirus infection has been reduced to its lowest on record. Wild poliovirus type …

Comment 714 www. thelancet. com Vol 400 September 3, 2022 risk of vaccine-associated
paralytic poliomyelitis caused by Sabin 2. 6 Although most countries eliminated Sabinlike …

Contrary to claims by T Jacob John and Dhanya Dharmapalan, 1 research demonstrates
that poliovirus transmission predominantly follows the oral-faecal route, 2 particularly in …

Polio eradication remains elusive, and its progress has been hampered by the COVID-19
pandemic. 1 Wild-type polioviruses are endemic in two countries (Afghanistan and …

The Global Polio Eradication Initiative owes much of its success in vastly reducing wild
poliovirus transmission globally to the use of live-attenuated Sabin oral poliovirus vaccine …

One of the outstanding scientific “endgame” questions for poliomyelitis eradication is how
long vaccine-related polioviruses will circulate after cessation of use of oral poliovirus …

The article describes how the international oversight body on polio eradication
recommended the rapid development, licensing, and introduction of a new monovalent type …

In The Lancet today, Roland Sutter and colleagues1 provide randomised data for a new
combination bivalent type 1 and 3 oral poliovirus vaccine (bOPV) in India. This vaccine will …

Ending Use of Oral Poliovirus Vaccine The global health community has taken the first step
toward eliminating use of oral poliovirus vaccine: switching from trivalent to bivalent vaccine …