Maternal obesity: new placental paradigms unfolded
C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …
Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
Human placental adaptive changes in response to maternal obesity: sex specificities
ED Santos, MH Hernández, V Sérazin… - International Journal of …, 2023 - mdpi.com
Maternal obesity is increasingly prevalent and is associated with elevated morbidity and
mortality rates in both mothers and children. At the interface between the mother and the …
mortality rates in both mothers and children. At the interface between the mother and the …
Maternal pre-pregnancy obesity is associated with altered placental transcriptome
Maternal obesity has a major impact on pregnancy outcomes. There is growing evidence
that maternal obesity has a negative influence on placental development and function …
that maternal obesity has a negative influence on placental development and function …
Programming of fetal insulin resistance in pregnancies with maternal obesity by ER stress and inflammation
F Westermeier, PJ Sáez… - BioMed Research …, 2014 - Wiley Online Library
The global epidemics of obesity during pregnancy and excessive gestational weight gain
(GWG) are major public health problems worldwide. Obesity and excessive GWG are related …
(GWG) are major public health problems worldwide. Obesity and excessive GWG are related …
Maternal obesity and the uterine immune cell landscape: the shaping role of inflammation
LE St-Germain, B Castellana, J Baltayeva… - International journal of …, 2020 - mdpi.com
Inflammation is often equated to the physiological response to injury or infection.
Inflammatory responses defined by cytokine storms control cellular mechanisms that can …
Inflammatory responses defined by cytokine storms control cellular mechanisms that can …
Feto-placental adaptations to maternal obesity in the baboon
D Farley, ME Tejero, AG Comuzzie, PB Higgins, L Cox… - Placenta, 2009 - Elsevier
Maternal obesity is present in 20–34% of pregnant women and has been associated with
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …
Placental dysfunction in obese women and antenatal surveillance
A Doshani, JC Konje - Best Practice & Research Clinical Obstetrics & …, 2023 - Elsevier
Obesity is a significant health concern worldwide and is associated with numerous health
complications, including placental dysfunction during pregnancy. Placental dysfunction can …
complications, including placental dysfunction during pregnancy. Placental dysfunction can …
Diabesity-associated oxidative and inflammatory stress signalling in the early human placenta
D Hoch, M Gauster, S Hauguel-de Mouzon… - Molecular aspects of …, 2019 - Elsevier
Early pregnancy is characterized by a series of complex and tightly regulated events to
ultimately establish implantation and early placental development. One of the key events is …
ultimately establish implantation and early placental development. One of the key events is …
Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity
J Saben, Y Zhong, H Gomez-Acevedo… - American Journal …, 2013 - journals.physiology.org
Obesity is associated with low-grade chronic inflammation, which contributes to cellular
dysfunction promoting metabolic disease. Obesity during pregnancy leads to a …
dysfunction promoting metabolic disease. Obesity during pregnancy leads to a …