Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

Astrocytes are the most numerous cell type in the brain and perform several essential
functions in supporting neuronal metabolism and actively participating in neural circuit and …

Increasing evidence has suggested that astrocytes demonstrate striking regionally allocated
functional heterogeneity. Here, we discuss how this spatiotemporally encoded diversity …

The complexity of neuronal networks cannot only be explained by neuronal activity so
neurobiological research in the last decade has focused on different components of the …

Astrocytes play key roles in CNS development as well as well as neuro-supportive roles in
the mature brain including ionic, bioenergetic and redox homeostasis. Astrocytes undergo …

Astrocytes tile the entire CNS. They are vital for neural circuit function, but have traditionally
been viewed as simple, homogenous cells that serve the same essential supportive roles …

There is increasing appreciation that non-neuronal cells contribute to the initiation,
progression and pathology of diverse neurodegenerative disorders. This Review focuses on …

Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

The past several decades have given rise to many important discoveries and novel insights
into the role of astrocytes in normal brain function and disease, firmly establishing concepts …

Despite the discovery of numerous molecules and pathologies, the pathophysiology of
various neurodegenerative diseases remains unknown. Genetics participates in the …