Acute kidney injury is usually associated with distant organ dysfunction. The roles of
inducible nitric oxide synthase (iNOS) and reactive oxygen species (ROS) in this …

Background: Renal ischemia-reperfusion (RIR) is a major cause of renal dysfunction that
acts through different mechanisms. We investigated the role of L-Arginine as an …

The functional abnormalities associated with unilateral postischemic acute renal failure in
the rat, as produced by 60 min of complete renal artery occlusion, are influenced by the …

This work studies the role that nitric oxide (NO) plays in ischemia/reperfusion (I/R) of the rat
kidney. Sprague-Dawley rats, weighing 250-300 g, were subjected to 75 min of warm …

Reactive oxygen and nitrogen species play a key role in the pathophysiology of renal
ischemia-reperfusion (I/R) injury. Recent studies have shown that nitrite (NO2−) serves as …

Objective: To study the role of the L‐arginine/nitric oxide (NO) pathway during renal
ischaemia‐reperfusion in rats. Design: Randomised experimental study. Setting: Teaching …

Contralateral uninephrectomy attenuates unilateral ischemic injury. The present work was
performed to elucidate whether the beneficial effect of uninephrectomy was associated with …

Renal ischemia/reperfusion (I/R) injury results in decreased glomerular filtration and renal
blood flow (RBF) and increased urine output, characterized by natriuresis and impaired …

Acute renal failure (ARF) following renal ischemia is characterized by changes in renal
hemodynamics, tubular obstruction, backleak of filtrate, and changes in vascular reactivity …

Salt-sensitive hypertension and chronic kidney disease (CKD) following recovery from acute
kidney injury (AKI) may occur secondary to incomplete repair, or by activation of circulating …