This study was carried out in order to examine whether the severity of acute renal failure
observed during the four hours following a 45 min period of unilateral occlusion of the renal …

Purpose: Acute kidney injury (AKI) induces acute lung injury (ALI) through releasing
injurious mediators or impairing clearance of systemic factors. To determine the links …

While tumor necrosis factor (TNF)-α is an important mediator of renal ischemia-reperfusion
(I/R) injury, its role in contralateral renal injury after isolated renal ischemia remains …

Tissue hypoxia has been proposed as an important event in renal ischemia-reperfusion
injury (IRI), particularly during the period of ischemia and in the immediate hours following …

Objective To determine the effect on nitric oxide (NO) release and renal NO synthase
(endothelial, eNOS and inducible, iNOS) activity of renal ischaemia‐reperfusion (I/R) in vivo …

The contributions of nitric oxide (NO) and renal blood flow (RBF) were examined in ischemia-
reperfusion injury in the rat kidney. The function of both kidneys was assessed by glomerular …

Nitric oxide synthase has been identified in several epithelial cells in the kidney, including
proximal tubular cells, thick ascending limb, inner medullary collecting duct, and interstitial …

Blockade of NO production is followed by an increase in leukocyte rolling and adhesion
resulting in some deleterious effects of ischemia. Preischemic administration of NO protects …

We have demonstrated previously that preischemic treatment with FK409 [(±)-(E)-4-ethyl-2-
[(E)-hydroxyimino]-5-nitro-3-hexenamide], a spontaneous nitric oxide (NO) donor, markedly …

The present study addressed the effect of interventions aimed to increase NO in the setting
of acute renal ischemia/reperfusion (I/R) in uninephrectomized rabbits. In the 60-minute post …