The present study addressed the effect of interventions aimed to increase NO in the setting
of acute renal ischemia/reperfusion (I/R) in uninephrectomized rabbits. In the 60-minute post …

Acute kidney injury (AKI) is a significant clinical problem associated with poor outcome. The
kidney, due to its inhomogeneous blood flow, is particularly susceptible to changes in …

The mechanisms by which nitric oxide (NO) exerts its protective effect in the
ischemia/reperfusion (I/R) injury of the kidney have not been fully determined. The …

We examined the contribution of nitric oxide (NO) to the effect of ischemic preconditioning
(IP) on renal function and the hemodynamics in ischemia-reperfusion (I/R) mediated kidney …

Background Regulation of renal hemodynamics--especially intraglomerular hemodynamics--
is closely related to the L-arginine (L-Arg)/nitric oxide (NO) pathway, both under basal …

Even though renal hypoxia is believed to play a pivotal role in the development of acute
kidney injury, no study has specifically addressed the alterations in renal oxygenation in the …

The objectives of this study were to compare the protective influence of exogenous nitric
oxide on renal ischemia reperfusion (I/R) injury with that of the antioxidant vitamins C and E …

Unilateral ischemia-reperfusion (UIR) injury leads to progressive renal atrophy and
tubulointerstitial fibrosis (TIF) and is commonly used to investigate the pathogenesis of the …

Postischemic acute renal failure is worsened when occurs in a various conditions with
impaired nitric oxide (NO) synthesis, such as arterial hypertension. Reoxygenation itself …

In this study we attempted to clarify the release of nitric oxide (NO) and its role in the
ischemia-reperfusion rat kidney. After right nephrectomy, male Wistar rats were divided into …