EFFECT OF INHIBITION OF NEURONAL NITRIC OXIDE SYNTHASE AND l‐ARGININE SUPPLEMENTATION ON RENAL ISCHAEMIA–REPERFUSION INJURY AND …

K Rusai, A Fekete, B Szebeni, Á Vannay… - Clinical and …, 2008 - Wiley Online Library
SUMMARY 1 The role of nitric oxide synthases (NOS) and the nitric oxide (NO) substrate l‐
arginine in renal ischaemia–reperfusion (I/R) has been studied extensively. However, the …

Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury

A Guven, B Uysal, O Akgul, H Cermik, G Gundogdu… - Renal failure, 2008 - Taylor & Francis
Introduction. Nitric oxide (NO) and peroxynitrite (OONO—) are implicated in the
pathophysiology of renal ischemia/reperfusion (I/R). The aim of this study was to investigate …

Oxidative and nitrosative stress in acute renal ischemia

E Noiri, A Nakao, K Uchida… - American Journal …, 2001 - journals.physiology.org
First Published July 12, 2001; 10.1152/ajprenal. 0071.2001.—Generation of reactive oxygen
species and nitric oxide in hypoxia-reperfusion injury may form a cytotoxic metabolite …

Renal protective effect of molsidomine and L-arginine in ischemia-reperfusion induced injury in rats

V Chander, K Chopra - Journal of Surgical Research, 2005 - Elsevier
BACKGROUND: Nitric oxide (NO), synthesized from l-arginine by the enzyme NO synthase
(NOS) seems to play an ambiguous role during tissue ischemia-reperfusion (I/R) injury. This …

Ozone oxidative preconditioning protects the rat kidney from reperfusion injury: the role of nitric oxide

H Chen, B Xing, X Liu, B Zhan, J Zhou, H Zhu… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: Ischemia/reperfusion (I/R) injury, which is commonly seen in the field of
renal surgery or transplantation, is a major cause of acute renal failure (ARF). Previous …

[PDF][PDF] The role of NO in renal ischemia-reperfusion injury in rats

G Hirabayashi - JOURNAL-TOKYO MEDICAL UNIVERSITY, 2000 - core.ac.uk
ABSTRACT INTRODUCTION: Direct and real-time measurement of nitric oxide (NO)
production has not been possible until recently because of its extremely short half-life …

Attenuation of renal ischemia-reperfusion injury in inducible nitric oxide synthase knockout mice

H Ling, C Edelstein, P Gengaro… - American Journal …, 1999 - journals.physiology.org
Renal ischemia-reperfusion (I/R) injury was investigated in inducible nitric oxide synthase
(iNOS) knockout mice. After a 26-min bilateral renal pedicle clamp, serum creatinine …

Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion

O Kwon, SM Hong, G Ramesh - American Journal of …, 2009 - journals.physiology.org
In postischemic acute kidney injury (AKI) or acute renal failure, a dissipation of glomerular
filtration pressure is associated with an altered renal vascular tone and reactivity, as well as …

Nitric oxide generation is increased in experimental renal warm ischaemia–reperfusion injury

SC Weight, PN Furness… - British journal of …, 1998 - Wiley Online Library
Background Nitric oxide has a clearly defined place in normal renal homoeostasis while
there is a continuing debate as to its role under pathophysiological conditions. This study …

PROTECTIVE EFFECT OF EXOGENOUS NITRIC OXIDE ON THE RENAL FUNCTION AND INFLAMMATORY RESPONSE IN A MODEL OF ISCHEMIA …

FJ Garcia-Criado, N Eleno, F Santos-Benito… - …, 1998 - journals.lww.com
Background. Tissue subjected to a period of ischemia undergoes morphological and
functional damage that increases during the reperfusion phase. The aim of the present work …