To assess the role of superoxide (O2−) and nitric oxide (NO) in ischaemic-reperfusion-
induced acute renal failure, we investigated whether an activation of the L-arginine-NO …

Contralateral uninephrectomy attenuates unilateral ischemic renal injury functionally and
morphologically. In this study we investigated the effects of uninephrectomy on apoptotic …

Endothelial dysfunction in ischemic acute renal failure (IARF) has been attributed to both
direct endothelial injury and to altered endothelial nitric oxide synthase (eNOS) activity, with …

In hypoxic and acidic tissue environments, nitrite is metabolised to nitric oxide, thus, bringing
about novel therapeutic options in myocardial infarction, peripheral artery disease, stroke …

This study was designed to examine if acute systemic blockade of nitric oxide (NO)
production by inhibition of nitric oxide synthase (NOS) with N-ω-nitro-L-arginine methyl ester …

Besides other mechanisms, nitric oxide (NO) plays a major role in maintaining the high renal
blood flow (RBF) and is also involved in the regulation of glomerular hemodynamics and …

Background Nitric oxide (NO) seems to play an important role during renal
ischemia/reperfusion (I/R) injury. We investigated whether rutin inhibits inducible nitric oxide …

Although acute renal ischaemia alters the production of various paracrines, there has been
little investigation examining the role of intrarenal vasoactive substances. In the present …

Introduction: Nitric oxide (NO), synthesized from l-arginine by the enzyme nitric oxide
synthase (NOS), seems to play an ambiguous role during tissue ischemia–reperfusion …

The natriuretic peptide (NP) system counter‐regulates the renin‐angiotensin system (RAS),
so enhancing the activity of natriuretic peptides (NPs) may be beneficial in conditions when …