Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes

JM Allen, AR Mackos, RM Jaggers, PC Brewster… - Gut …, 2022 - Taylor & Francis
Psychological stress alters the gut microbiota and predisposes individuals to increased risk
for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are …

Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota

JD Galley, MC Nelson, Z Yu, SE Dowd, J Walter… - BMC microbiology, 2014 - Springer
Background The microbiota of the mammalian gastrointestinal (GI) tract consists of diverse
populations of commensal bacteria that interact with host physiological function …

Chronic psychological stress disrupted the composition of the murine colonic microbiota and accelerated a murine model of inflammatory bowel disease

Y Watanabe, S Arase, N Nagaoka, M Kawai… - PloS one, 2016 - journals.plos.org
The effect of psychological stress on the gastrointestinal microbiota is widely recognized.
Chronic psychological stress may be associated with increased disease activity in …

Stress and antibiotics alter luminal and wall‐adhered microbiota and enhance the local expression of visceral sensory‐related systems in mice

M Aguilera, P Vergara… - Neurogastroenterology & …, 2013 - Wiley Online Library
Background Stress leads to altered gastrointestinal neuro‐immune responses. We
characterized the interaction between stress and gut commensal microbiota and their role …

Influence of stressor-induced nervous system activation on the intestinal microbiota and the importance for immunomodulation

MT Bailey - Microbial endocrinology: the microbiota-gut-brain axis …, 2014 - Springer
The body is colonized by a vast population of genetically diverse microbes, the majority of
which reside within the intestines to comprise the intestinal microbiota. During periods of …

[HTML][HTML] Effects of psychological, environmental and physical stressors on the gut microbiota

JP Karl, AM Hatch, SM Arcidiacono… - Frontiers in …, 2018 - frontiersin.org
Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation

MT Bailey, SE Dowd, JD Galley, AR Hufnagle… - Brain, behavior, and …, 2011 - Elsevier
The bodies of most animals are populated by highly complex and genetically diverse
communities of microorganisms. The majority of these microbes reside within the intestines …

Gut microbiota are associated with psychological stress-induced defections in intestinal and blood–brain barriers

S Geng, L Yang, F Cheng, Z Zhang, J Li, W Liu… - Frontiers in …, 2020 - frontiersin.org
Altered gut microbiota has been identified during psychological stress, which causes severe
health issues worldwide. The integrity of the intestinal barrier and blood–brain barrier …

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors

SC Pearce, HG Coia, JP Karl… - Frontiers in …, 2018 - frontiersin.org
The gut microbiome is extremely important for maintaining homeostasis with host intestinal
epithelial, neuronal, and immune cells and this host-microbe interaction is critical during …

Impact of stressor exposure on the interplay between commensal microbiota and host inflammation

JD Galley, MT Bailey - Gut microbes, 2014 - Taylor & Francis
Exposure to stressful stimuli results in the activation of multiple physiological processes
aimed at maintaining homeostasis within the body. These physiological processes also …