Molecular monitoring for patients with chronic myeloid leukaemia (CML) has become an
important practice in the era of imatinib therapy. For successful widespread introduction into …

BACKGROUND AND OBJECTIVES: The most common translocation in chronic myeloid
leukemia (CML) t (9; 22)(q34; q22) produces the BCR/ABL fusion gene. We set up and …

Background: Current practice guidelines for managing patients with chronic myelogenous
leukemia (CML) call for monitoring BCR-ABL transcript concentrations with a quantitative …

Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …

Molecular monitoring of chronic myeloid leukaemia (CML) patients by real time quantitative
reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory …

An international basis for comparison of BCR-ABL mRNA levels is required for the common
interpretation of data derived from individual laboratories. This will aid clinical decisions for …

Serial quantification of BCR-ABL1 messenger RNA (mRNA) is an important therapeutic
indicator for patients with chronic myeloid leukemia, but historically, there has been …

The high efficacy of the standard treatment of chronic myeloid leukemia (CML) with imatinib
has prompted the need for accurate methods to monitor response at levels below the …

Serial quantitation of BCR-ABL mRNA levels is an important indicator of therapeutic
response for patients with chronic myelogenous leukemia and Philadelphia chromosome …

In patients with chronic myeloid leukemia, the use of real-time quantitative reverse
transcription-polymerase chain reaction (qRT-PCR) for measuring BCR-ABL1 transcripts …