Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia
Molecular monitoring for patients with chronic myeloid leukaemia (CML) has become an
important practice in the era of imatinib therapy. For successful widespread introduction into …
important practice in the era of imatinib therapy. For successful widespread introduction into …
Real-time quantification of different types of bcr-abl transcript in chronic myeloid leukemia
M Amabile, B Giannini, N Testoni, V Montefusco… - …, 2001 - haematologica.org
BACKGROUND AND OBJECTIVES: The most common translocation in chronic myeloid
leukemia (CML) t (9; 22)(q34; q22) produces the BCR/ABL fusion gene. We set up and …
leukemia (CML) t (9; 22)(q34; q22) produces the BCR/ABL fusion gene. We set up and …
Development of an Integrated Assay for Detection of BCR-ABL RNA
ES Winn-Deen, B Helton, R Van Atta, W Wong… - Clinical …, 2007 - academic.oup.com
Background: Current practice guidelines for managing patients with chronic myelogenous
leukemia (CML) call for monitoring BCR-ABL transcript concentrations with a quantitative …
leukemia (CML) call for monitoring BCR-ABL transcript concentrations with a quantitative …
Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time'quantitative RT-PCR assay
C Preudhomme, F Revillion, A Merlat, L Hornez… - Leukemia, 1999 - nature.com
Quantitative competitive RT-PCR techniques have been developed to detect BCR-ABL
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …
fusion transcripts in CML but they are hardly reproducible. In this work, we have developed …
Standardisation of molecular monitoring for chronic myeloid leukaemia
NCP Cross - Best practice & research Clinical haematology, 2009 - Elsevier
Molecular monitoring of chronic myeloid leukaemia (CML) patients by real time quantitative
reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory …
reverse transcriptase PCR (RQ-PCR) is of clinical value, but the use of diverse laboratory …
Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response …
S Branford, L Fletcher, NCP Cross… - Blood, The Journal …, 2008 - ashpublications.org
An international basis for comparison of BCR-ABL mRNA levels is required for the common
interpretation of data derived from individual laboratories. This will aid clinical decisions for …
interpretation of data derived from individual laboratories. This will aid clinical decisions for …
Molecular monitoring of chronic myeloid leukemia: principles and interlaboratory standardization
NCP Cross, A Hochhaus, MC Müller - Annals of hematology, 2015 - Springer
Serial quantification of BCR-ABL1 messenger RNA (mRNA) is an important therapeutic
indicator for patients with chronic myeloid leukemia, but historically, there has been …
indicator for patients with chronic myeloid leukemia, but historically, there has been …
Harmonization of molecular monitoring of CML therapy in Europe
MC Müller, NCP Cross, P Erben, T Schenk, B Hanfstein… - Leukemia, 2009 - nature.com
The high efficacy of the standard treatment of chronic myeloid leukemia (CML) with imatinib
has prompted the need for accurate methods to monitor response at levels below the …
has prompted the need for accurate methods to monitor response at levels below the …
Establishment of the first World Health Organization International Genetic Reference Panel for quantitation of BCR-ABL mRNA
HE White, P Matejtschuk, P Rigsby… - Blood, The Journal …, 2010 - ashpublications.org
Serial quantitation of BCR-ABL mRNA levels is an important indicator of therapeutic
response for patients with chronic myelogenous leukemia and Philadelphia chromosome …
response for patients with chronic myelogenous leukemia and Philadelphia chromosome …
Inter-laboratory comparison of chronic myeloid leukemia minimal residual disease monitoring: summary and recommendations
T Zhang, S Grenier, B Nwachukwu, C Wei… - The Journal of Molecular …, 2007 - Elsevier
In patients with chronic myeloid leukemia, the use of real-time quantitative reverse
transcription-polymerase chain reaction (qRT-PCR) for measuring BCR-ABL1 transcripts …
transcription-polymerase chain reaction (qRT-PCR) for measuring BCR-ABL1 transcripts …