A new quantitative method, †œSimultaneousExponential Equation method―(SEE), has
been developed for the analysis of pulmonary ventilation studies using 13N-labeled …

Measurement of alveolar volume (Va) and regional ventilation (V̇a) is crucial to
understanding the pathophysiology of acute lung injury and ventilator-induced lung injury …

A mathematical model was developed to estimate right-to-left shunt (Fs) and the volume of
distribution of 13NN in alveolar gas (VA) and shunt tissue (Vs). The data obtained from this …

Regional changes in ventilation and perfusion occurring in the early hours after smoke
inhalation injury were evaluated through the use of positron emission tomography. Five …

Regional specific lung volume change (sVol), defined as the regional tidal volume divided
by the regional end-expiratory gas volume, is a key variable in lung mechanics and in the …

MATERIALSAND METhODS PETStudy Subjectsconsistedof four healthymalevolunteers,
35— 50yr old (mean ±sd, 41 ±7). Following a 10-mmtransmissionscan to correctfor …

Several methods allow regional gas exchange to be inferred from imaging of regional
ventilation and perfusion (V/Q) ratios. Each method measures slightly different aspects of …

Cigarette smoke is thought to promote local lung inflammation that leads to lung dysfunction.
Lung neutrophilic inflammation is known to result in increased pulmonary uptake of 18F …

The adaptation to positron emission tomography of the steady-state technique for the
measurement of alveolar ventilation, based on the shortlived radionuclide neon-19 (T,= 17.4 …

Gallium-68 (68 Ga) is a positron-emitting radionuclide suitable for positron emission
tomography (PET) imaging that has a number of convenient features—it has a physical half …