[HTML][HTML] FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis

W Hu, C Zhou, Q Jing, Y Li, J Yang, C Yang… - Cancer Cell …, 2021 - Springer
Background Ferroptosis is a newly identified type of programmed cell death, which
preferentially targets iron-rich cancer cells such as hepatocellular carcinoma (HCC). Ferritin …

Molecular targets of ferroptosis in hepatocellular carcinoma

H Liao, J Shi, K Wen, J Lin, Q Liu, B Shi… - Journal of …, 2021 - Taylor & Francis
Ferroptosis is a special form of regulatory cell death caused by the accumulation of
intracellular iron and lipid peroxidation. Here, we summarize the research progress on …

[HTML][HTML] Targeting ferroptosis pathway to combat therapy resistance and metastasis of cancer

X Liu, Y Zhang, X Wu, F Xu, H Ma, M Wu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …

[HTML][HTML] Novel insights on targeting ferroptosis in cancer therapy

S Zuo, J Yu, H Pan, L Lu - Biomarker Research, 2020 - Springer
Ferroptosis belongs to a novel form of regulated cell death. It is characterized by iron
dependence, destruction of intracellular redox balance and non-apoptosis. And cellular …

[HTML][HTML] Iron and magnetic: new research direction of the ferroptosis-based cancer therapy

S Wang, J Luo, Z Zhang, D Dong, Y Shen… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Ferroptosis is an iron depend cell death which caused by lipid peroxidation. Abnormal iron
metabolism and high intracellular iron content are the characteristics of most cancer cells …

[HTML][HTML] Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types

B Tang, R Yan, J Zhu, S Cheng, C Kong… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Ferroptosis is a recently described mode of cell death caused by the accumulation of
intracellular iron and lipid reactive oxygen species (ROS), which play critical roles in …

[HTML][HTML] Ferroptosis: a new hunter of hepatocellular carcinoma

Y Jiang, Y Yu, Z Pan, C Glandorff, M Sun - Cell Death Discovery, 2024 - nature.com
Ferroptosis is an iron ion-dependent, regulatory cell death modality driven by intracellular
lipid peroxidation that plays a key role in the development of HCC. Studies have shown that …

[HTML][HTML] Ferroptosis: from basic research to clinical therapeutics in hepatocellular carcinoma

Z Huang, H Xia, Y Cui, JWP Yam… - Journal of Clinical and …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common and highly heterogeneous
malignancies worldwide. Despite the rapid development of multidisciplinary treatment and …

[HTML][HTML] The critical role of ferroptosis in hepatocellular carcinoma

F Pan, X Lin, L Hao, T Wang, H Song… - Frontiers in Cell and …, 2022 - frontiersin.org
Liver cancer is the sixth most frequently diagnosed cancer and the third dominant cause of
cancer death worldwide. Ferroptosis is characterized as an iron-dependent form of …

[HTML][HTML] Targeting ferroptosis for cancer therapy: exploring novel strategies from its mechanisms and role in cancers

M Jiang, M Qiao, C Zhao, J Deng, X Li… - … lung cancer research, 2020 - ncbi.nlm.nih.gov
Ferroptosis is a novel form of non-apoptotic regulated cell death (RCD), with distinct
characteristics and functions in physical conditions and multiple diseases such as cancers …