Cost-effectiveness of urinary biomarker panel in prostate cancer risk assessment

TM Govers, L Caba, MJ Resnick - The Journal of urology, 2018 - Elsevier
Purpose SelectMDx (MDxHealth®) is a panel of urinary biomarkers used in conjunction with
traditional risk factors to individualize risk prediction for clinically significant prostate cancer …

Cost‐effectiveness of a new urinary biomarker‐based risk score compared to standard of care in prostate cancer diagnostics–a decision analytical model

S Dijkstra, TM Govers, RJ Hendriks… - BJU …, 2017 - Wiley Online Library
Objective To assess the cost‐effectiveness of a new urinary biomarker‐based risk score
(Select MD x; MD xHealth, Inc., Irvine, CA, USA) to identify patients for transrectal …

Incorporating biomarkers into the primary prostate biopsy setting: a cost-effectiveness analysis

NJ Sathianathen, KM Kuntz, F Alarid-Escudero… - Journal of …, 2018 - journals.lww.com
Purpose: We performed a cost-effectiveness analysis using the PHI (Prostate Health Index),
4Kscore®, SelectMDx™ and the EPI (ExoDx™ Prostate [IntelliScore]) in men with elevated …

Urinary molecular biomarker test impacts prostate biopsy decision making in clinical practice

N Shore, J Hafron, T Langford, M Stein, J DeHart… - Urology …, 2019 - auajournals.org
Introduction: There is an unmet need for noninvasive methods to better identify patients at
increased risk for clinically significant prostate cancer. SelectMDx® is a molecular urine test …

The state of the science on prostate cancer biomarkers: the San Francisco consensus statement

MR Cooperberg, PR Carroll, MA Dall'Era, BJ Davies… - European urology, 2019 - Elsevier
At every point along the prostate cancer continuum of care, from early detection through to
advanced disease, a man must face decisions that may have a direct impact on his long …

Biomarkers for Pre-Treatment Risk Stratification of Prostate Cancer Patients: A Systematic Review

JP Sequeira, S Salta, R Freitas, R López-López… - Cancers, 2024 - mdpi.com
Simple Summary PCa remains a leading health concern worldwide. Serum PSA-based PCa
screening led to a well-documented decreased mortality but at the cost of the increased …

Whom to biopsy: prediagnostic risk stratification with biomarkers, nomograms, and risk calculators

S Loeb, H Dani - Urologic Clinics, 2017 - urologic.theclinics.com
Historically, prostate biopsy was performed because of a prostate-specific antigen (PSA)
level exceeding a specific threshold or suspicious findings on digital rectal examination …

Two-stage biomarker protocols for improving the precision of early detection of prostate cancer

CL Barnett, SA Tomlins, DJ Underwood… - Medical Decision …, 2017 - journals.sagepub.com
Background. New cancer biomarkers are being discovered at a rapid pace; however, these
tests vary in their predictive performance characteristics, and it is unclear how best to use …

Novel biomarkers for prostate cancer: an evidence‐based review for use in clinical practice

VM Narayan, BR Konety… - International Journal of …, 2017 - Wiley Online Library
Prostate cancer is a heterogeneous disease with disparate outcomes. Traditional clinical
parameters are limited in their ability to differentiate between these cases, and there is …

[HTML][HTML] The use of biomarkers in prostate cancer screening and treatment

AV Alford, JM Brito, KK Yadav, SS Yadav… - Reviews in …, 2017 - ncbi.nlm.nih.gov
Prostate cancer screening and diagnosis has been guided by prostate-specific antigen
levels for the past 25 years, but with the most recent US Preventive Services Task Force …