Targeted therapies against the Epidermal Growth Factor Receptor (EGFR) are useful to treat
many human cancers such as non-small cell lung cancer, colorectal cancer and head and …

Purpose: The epidermal growth factor receptor (EGFR) is recognized as a key mediator of
proliferation and progression in many human tumors. A series of EGFR-specific inhibitors …

Abstract 5333 Although molecular inhibitors of EGFR signaling carry high promise in cancer
therapeutics, clinical trial results to date indicate that only a small subset of patients (10 …

Mechanisms of Intrinsic and Acquired Resistance to EGFR Inhibitors Page 1 276 Current Cancer
Therapy Reviews, 2007, 3, 276-283 1573-3947/07 $50.00+.00 © 2007 Bentham Science …

The epidermal growth factor receptor (EGFR) is a validated molecular target in squamous
cell carcinoma of the head and neck (HNSCC). However, despite high expression levels of …

Targeted therapies that inhibit the activity of tyrosine kinase receptors such as the epidermal
growth factor receptor (EGFR) have shown activity against solid malignancies when used as …

The epidermal growth factor receptor (EGFR) has been a major target of molecular
anticancer therapy. Two approaches have been developed, involving monoclonal …

The epidermal growth factor receptor (EGFR) is widely expressed in head and neck
squamous cell carcinomas (HNSCC) and activates many growth and survival pathways …

The epidermal growth factor receptor (EGFR) is widely expressed in head and neck
squamous cell carcinomas (HNSCC) and can activate many growth and survival pathways …

The epidermal growth factor receptor (EGFR) autocrine pathway plays a crucial role in
human cancer, contributing to a number of highly relevant processes in tumor development …