Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways

X Chen, W Ma, Y Yao, Q Zhang, J Li, X Wu, C Mei… - Cell death & …, 2021 - nature.com
Serum deprivation-response protein (SDPR), a phosphatidylserine-binding protein, which is
known to have a promising role in caveolar biogenesis and morphology. However, its …

Serum deprivation response inhibits breast cancer progression by blocking transforming growth factor‐β signaling

Y Tian, Y Yu, LK Hou, JR Chi, JF Mao, L Xia… - Cancer …, 2016 - Wiley Online Library
Serum deprivation response (SDPR), a key substrate for protein kinase C, play a critical role
in inducing membrane curvature and participate in the formation of caveolae. However, the …

The humanserum deprivation responsegene (sdpr) maps to 2q32–q33 and codes for a phosphatidylserine-binding protein

S Gustincich, P Vatta, S Goruppi, M Wolf, S Saccone… - Genomics, 1999 - Elsevier
Theserum deprivation responsegene (SDPR, aliassdr) has been previously isolated for its
high mRNA expression in serum-starved cells compared to contact-inhibited NIH3T3 cells; …

DAPK–HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells

N Benderska, J Ivanovska, TT Rau… - Journal of Cell …, 2014 - journals.biologists.com
Death-associated protein kinase (DAPK) is a serine-threonine kinase with tumor suppressor
function. Previously, we demonstrated that tumor necrosis factor (TNF) induced DAPK …

Novel tumor suppressor SPRYD4 inhibits tumor progression in hepatocellular carcinoma by inducing apoptotic cell death

KR Zahid, S Han, F Zhou, U Raza - Cellular Oncology, 2019 - Springer
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-
associated deaths worldwide. Although recent studies have proposed different biomarkers …

Downregulation of protein disulfide‑isomerase A3 expression inhibits cell proliferation and induces apoptosis through STAT3 signaling in hepatocellular carcinoma

R Kondo, K Ishino, R Wada… - International …, 2019 - spandidos-publications.com
Protein disulfide‑isomerase A3 (PDIA3) is a chaperone protein that modulates folding of
newly synthesized glycoproteins and responds to endoplasmic reticulum (ER) stress …

S1PR1 promotes proliferation and inhibits apoptosis of esophageal squamous cell carcinoma through activating STAT3 pathway

Y Liu, Y Zhi, H Song, M Zong, J Yi, G Mao… - Journal of Experimental …, 2019 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the most common
cancers worldwide, which lacks effective biomarkers for prognosis. Therefore, it is urgent to …

SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis

S Ozturk, P Papageorgis, CK Wong… - Proceedings of the …, 2016 - National Acad Sciences
Metastatic dissemination of breast cancer cells represents a significant clinical obstacle to
curative therapy. The loss of function of metastasis suppressor genes is a major rate-limiting …

SERP1 is a novel marker of poor prognosis in pancreatic ductal adenocarcinoma patients via anti-apoptosis and regulating SRPRB/NF-κB axis

Q Ma, X Wu, J Wu, Z Liang… - … journal of oncology, 2017 - spandidos-publications.com
Stress associated endoplasmic reticulum protein 1 (SERP1), can cause accumulation of
unfolded proteins in ER stress. However, studies on the role of SERP1 in pancreatic ductal …

Suppression of MG132-mediated cell death by peroxiredoxin 1 through influence on ASK1 activation in human thyroid cancer cells

ZX Du, Y Yan, HY Zhang, BQ Liu… - Endocrine-related …, 2010 - erc.bioscientifica.com
Proteasome inhibitors represent a novel class of antitumor agents with pre-clinical and
clinical evidence of activity against hematologic malignancies and solid tumors. However …