Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity
B Stijlemans, G Caljon, J Van Den Abbeele… - Frontiers in …, 2016 - frontiersin.org
The diseases caused by African trypanosomes (AT) are of both medical and veterinary
importance and have adversely influenced the economic development of sub-Saharan …
importance and have adversely influenced the economic development of sub-Saharan …
Escaping deleterious immune response in their hosts: lessons from trypanosomatids
A Geiger, G Bossard, D Sereno, J Pissarra… - Frontiers in …, 2016 - frontiersin.org
The Trypanosomatidae family includes the genera Trypanosoma and Leishmania,
protozoan parasites displaying complex digenetic life cycles requiring a vertebrate host and …
protozoan parasites displaying complex digenetic life cycles requiring a vertebrate host and …
Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake
J Cnops, S Magez, C De Trez - Parasitology, 2015 - cambridge.org
African trypanosomes have been around for more than 100 million years, and have adapted
to survival in a very wide host range. While various indigenous African mammalian host …
to survival in a very wide host range. While various indigenous African mammalian host …
Host immune responses and immune evasion strategies in African trypanosomiasis
C Onyilagha, JE Uzonna - Frontiers in immunology, 2019 - frontiersin.org
Parasites, including African trypanosomes, utilize several immune evasion strategies to
ensure their survival and completion of their life cycles within their hosts. The defense factors …
ensure their survival and completion of their life cycles within their hosts. The defense factors …
How the African trypanosomes evade host immune killing
B Namangala - Parasite immunology, 2011 - Wiley Online Library
Unlike other protozoan parasites, African trypanosomes never enter the host cell at any
stage of their development. Instead, these parasites swim freely in the immunologically …
stage of their development. Instead, these parasites swim freely in the immunologically …
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune …
S Magez, JE Pinto Torres, E Obishakin… - Frontiers in …, 2020 - frontiersin.org
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game
animals around the world. Through co-evolution with the mammalian immune system …
animals around the world. Through co-evolution with the mammalian immune system …
The within-host dynamics of African trypanosome infections
KR Matthews, R McCulloch… - … Transactions of the …, 2015 - royalsocietypublishing.org
African trypanosomes are single-celled protozoan parasites that are capable of long-term
survival while living extracellularly in the bloodstream and tissues of mammalian hosts …
survival while living extracellularly in the bloodstream and tissues of mammalian hosts …
African trypanosomes undermine humoral responses and vaccine development: link with inflammatory responses?
B Stijlemans, M Radwanska, C De Trez… - Frontiers in …, 2017 - frontiersin.org
African trypanosomosis is a debilitating disease of great medical and socioeconomical
importance. It is caused by strictly extracellular protozoan parasites capable of infecting all …
importance. It is caused by strictly extracellular protozoan parasites capable of infecting all …
An Overview of Trypanosoma brucei Infections: An Intense Host–Parasite Interaction
A Ponte-Sucre - Frontiers in microbiology, 2016 - frontiersin.org
Trypanosoma brucei rhodesiense and T. brucei gambiense, the causative agents of Human
African Trypanosomiasis, are transmitted by tsetse flies. Within the vector, the parasite …
African Trypanosomiasis, are transmitted by tsetse flies. Within the vector, the parasite …
Mouse models for pathogenic African trypanosomes: unravelling the immunology of host–parasite–vector interactions
S Magez, G Caljon - Parasite Immunology, 2011 - Wiley Online Library
African trypanosomiasis is a parasitic disease that affects a variety of mammals, including
humans, on the sub‐Saharan African continent. To understand the diverse parameters that …
humans, on the sub‐Saharan African continent. To understand the diverse parameters that …