Human cancers exhibit genomic instability and an increased mutation rate due to underlying
defects in DNA repair. Cancer cells are often defective in one of six major DNA repair …

Background & Aims: How specifically to treat pancreatic and other cancers harboring
Fanconi anemia gene mutations has raised great interest recently, yet preclinical studies …

Persistent dysregulation of the DNA damage response and repair in cells causes genomic
instability. The resulting genetic changes permit alterations in growth and proliferation …

Fanconi anemia (FA) is a cancer predisposition disorder characterized by progressive bone
marrow failure, congenital developmental defects, chromosomal abnormalities, and cellular …

Fanconi anaemia (FA) is a rare genetic cancer-susceptibility syndrome that is characterized
by congenital abnormalities, bone-marrow failure and cellular sensitivity to DNA crosslinking …

Fanconi anemia is a genetic disorder that is characterized by bone marrow failure, as well
as a predisposition to malignancies including leukemia and squamous cell carcinoma …

Purpose Mutations in genes involved in Fanconi anemia (FA)/BRCA DNA repair pathway
cause cancer susceptibility diseases including familial breast cancer and Fanconi anemia …

A rare genetic disease, Fanconi anemia (FA), now attracts broader attention from cancer
biologists and basic researchers in the DNA repair and ubiquitin biology fields as well as …

Fanconi anemia (FA) is a rare inherited recessive disease caused by mutations in one of
fifteen genes known to encode FA pathway components. In response to DNA damage …

Colorectal cancer (CRC) is one of the most common neoplasms in the world. Fanconi
anemia (FA) is a very rare genetic disease causing bone marrow failure, congenital growth …