Although rhabdomyolysis-associated acute kidney injury (AKI) is a life-threatening clinical
condition that accounts for about 10–40% of AKI cases, the mechanism underlying …

Acute kidney injury (AKI) is one of the most severe complications of rhabdomyolysis (RM).
The underlying mechanisms and potential preventions need to be investigated …

Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …

Background: Rhabdomyolysis (RM) is a clinical syndrome characterized by breakdown of
skeletal muscle fibers and release of their contents into the circulation. Myoglobin-induced …

Acute kidney injury (AKI) is a life-threatening complication of rhabdomyolysis. The
pathophysiological mechanisms of rhabdomyolysis-induced AKI (RIAKI) have been …

Introduction: A recent study showed that early renal tubular injury is ameliorated in Nod-like
receptor pyrin domain-containing protein 3 (NLRP3) KO mice with rhabdomyolysis-induced …

Background Acute kidney injury (AKI) is the most severe complication of rhabdomyolysis.
Allopurinol (Allo), a xanthine oxidase inhibitor, has been in the spotlight in the last decade …

Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

Aims Rhabdomyolysis (RM) is a critical condition with a high mortality rate, but effective
management is still deficient. Till date, there are no studies that have addressed the effect of …

Objective To investigate whether apoptosis of renal tubular epithelial cells induced by
endoplasmic reticulum stress (ERS) takes a role in the traumatic rhabdomyolysis-induced …