[HTML][HTML] The use of 'omics for diagnosing and predicting progression of chronic kidney disease: A scoping review

MA Govender, JT Brandenburg, J Fabian… - Frontiers in …, 2021 - frontiersin.org
Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality.
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …

[HTML][HTML] Pathophysiologic mechanisms and potential biomarkers in diabetic kidney disease

CY Jung, TH Yoo - Diabetes & Metabolism Journal, 2022 - ncbi.nlm.nih.gov
Although diabetic kidney disease (DKD) remains the leading cause of end-stage kidney
disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD …

Transcriptomics: a step behind the comprehension of the polygenic influence on oxidative stress, immune deregulation, and mitochondrial dysfunction in chronic …

S Granata, A Dalla Gassa, G Bellin… - BioMed Research …, 2016 - Wiley Online Library
Chronic kidney disease (CKD) is an increasing and global health problem with a great
economic burden for healthcare system. Therefore to slow down the progression of this …

Metabolic biomarkers for chronic kidney disease

M Breit, KM Weinberger - Archives of biochemistry and biophysics, 2016 - Elsevier
Chronic kidney disease (CKD) is an increasingly recognized burden for patients and health
care systems with high (and growing) global incidence and prevalence, significant mortality …

Omics in chronic kidney disease: focus on prognosis and prediction

M Provenzano, R Serra, C Garofalo, A Michael… - International Journal of …, 2021 - mdpi.com
Chronic kidney disease (CKD) patients are characterized by a high residual risk for
cardiovascular (CV) events and CKD progression. This has prompted the implementation of …

Integrated multi-omics approaches to improve classification of chronic kidney disease

S Eddy, LH Mariani, M Kretzler - Nature Reviews Nephrology, 2020 - nature.com
Chronic kidney diseases (CKDs) are currently classified according to their clinical features,
associated comorbidities and pattern of injury on biopsy. Even within a given classification …

Proteomics and metabolomics in kidney disease, including insights into etiology, treatment, and prevention

RF Dubin, EP Rhee - Clinical Journal of the American Society of …, 2020 - journals.lww.com
In this review of the application of proteomics and metabolomics to kidney disease research,
we review key concepts, highlight illustrative examples, and outline future directions. The …

Omics research in diabetic kidney disease: new biomarker dimensions and new understandings?

N Tofte, F Persson, P Rossing - Journal of nephrology, 2020 - Springer
The use of “omics” is increasing in research areas looking to identify biomarkers or early
preclinical signs of disease or to increase understanding of complex pathological processes …

New potential biomarkers for chronic kidney disease management—A review of the literature

I Lousa, F Reis, I Beirão, R Alves, L Belo… - International Journal of …, 2020 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

Chronic kidney disease: biomarker diagnosis to therapeutic targets

YN Wang, SX Ma, YY Chen, L Chen, BL Liu, QQ Liu… - Clinica Chimica …, 2019 - Elsevier
Chronic kidney disease (CKD), characterized as renal dysfunction, is recognized as a major
public health problem with high morbidity and mortality worldwide. Unfortunately, there are …