Cellular mechanisms underlying the cardiovascular actions of oestrogens

S Ling, P Komesaroff, K Sudhir - Clinical Science, 2006 - portlandpress.com
Although pre-menopausal women enjoy relative cardiovascular protection, hormone
(oestrogen±progestin)-replacement therapy has not shown cardiovascular benefits in post …

The heart as a target for oestrogens

L Brown, I Hoong, SA Doggrell - Heart Lung & Circulation, 2000 - Wiley Online Library
Observational studies have consistently shown a markedly decreased risk of cardiovascular
disease in postmenopausal women when treated with oestrogens. This review discusses …

Sex steroids and the endothelium

HW Schnaper, J McGuire, C Runyan… - Current medicinal …, 2000 - ingentaconnect.com
Gonadal steroids clearly influence the course of atherosclerotic cardiovascular disease in
women. This observation has suggested that these hormones have beneficial effects on the …

Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women

S Novella, D Pérez‐Cremades… - The Journal of …, 2019 - Wiley Online Library
Women show a lower incidence of cardiovascular diseases than age‐matched men, but this
benefit disappears after menopause. Oestrogen‐mediated vascular actions are mainly …

Estrogen in cardiovascular disease

W Zhu, WV Everson, EJ Smart - Current opinion in lipidology, 2004 - journals.lww.com
Estrogens, like other steroid hormones, are potent actors in the cardiovascular system. Since
half the population have high levels of estrogen most of their lives it is plain that estrogen …

Estrogen in vascular smooth muscle cells: A friend or a foe?

H Dehaini, M Fardoun, H Abou-Saleh, A El-Yazbi… - Vascular …, 2018 - Elsevier
Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. The
effect of estrogen on these diseases has been assessed in in vitro and in vivo models, as …

The role of estrogen and estrogen receptors on cardiomyocytes: an overview

T Luo, JK Kim - Canadian Journal of Cardiology, 2016 - Elsevier
Sex differences in the onset and manifestation of cardiovascular diseases are well known,
yet the mechanism behind this discrepancy remains obscure. Estrogen and its …

Postmenopausal oestrogen replacement therapy and atherosclerosis: can current compounds provide cardiovascular protection?

M Barton - Expert opinion on investigational drugs, 2001 - Taylor & Francis
The natural oestrogen, 17β-oestradiol, has been implicated in protection from
atherosclerosis, a chronic systemic vascular disease with an inflammatory component …

[HTML][HTML] Signalling mechanisms in the cardiovascular protective effects of estrogen: With a focus on rapid/membrane signalling.

AR Niță, GA Knock, RJ Heads - Current Research in Physiology, 2021 - Elsevier
In modern society, cardiovascular disease remains the biggest single threat to life, being
responsible for approximately one third of worldwide deaths. Male prevalence is significantly …

The role of estrogen and estrogen-related drugs in cardiovascular diseases

H Ogita, K Node, M Kitakaze - Current drug metabolism, 2003 - ingentaconnect.com
The cardiovascular effects of estrogen have recently become a focus of basic and clinical
cardiovascular medicine because of the multiplicity of its beneficial effects. Various basic …