The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy
Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
Estrogens in vascular biology and disease: where do we stand today?
JF Arnal, PY Scarabin, F Trémollières… - Current Opinion in …, 2007 - journals.lww.com
Estrogens in vascular biology and disease: where do we stand... : Current Opinion in
Lipidology Estrogens in vascular biology and disease: where do we stand today? : Current …
Lipidology Estrogens in vascular biology and disease: where do we stand today? : Current …
Animal models of the cardiovascular effects of exogenous hormones
RH Karas - The American journal of cardiology, 2002 - Elsevier
As early as the 1950s, animal studies showed that exogenous estrogen could inhibit
coronary atherosclerosis. Since then, additional animal studies have helped to further …
coronary atherosclerosis. Since then, additional animal studies have helped to further …
17β-Estradiol inhibits proliferation and migration of human vascular smooth muscle cells: similar effects in cells from postmenopausal females and in males
D Dai-Do, E Espinosa, G Liu, TJ Rabelink… - Cardiovascular …, 1996 - academic.oup.com
Objectives: Cardiovascular disease is rare in premenopausal women, but increases after the
menopause when hormone replacement therapy reduces coronary events. Vascular smooth …
menopause when hormone replacement therapy reduces coronary events. Vascular smooth …
Sex hormone replacement therapy and modulation of vascular function in cardiovascular disease
VV Koledova, RA Khalil - Expert Review of Cardiovascular …, 2007 - Taylor & Francis
Epidemiological and experimental studies suggest vascular protective effects of estrogen.
Cardiovascular disease (CVD) is less common in premenopausal women than in men and …
Cardiovascular disease (CVD) is less common in premenopausal women than in men and …
Various actions of oestrogens on the vascular system
JC Stevenson - Maturitas, 1998 - Elsevier
Epidemiological studies show a reduction in cardiovascular disease with postmenopausal
oestrogen use. Oestrogens have been shown to have both metabolic effects and direct …
oestrogen use. Oestrogens have been shown to have both metabolic effects and direct …
Understanding the controversy about hormonal replacement therapy: insights from estrogen effects on experimental and clinical atherosclerosis.
JF Arnal, V Douin-Echinard, F Tremollières… - … des Maladies du …, 2007 - europepmc.org
Whereas hormonal replacement/menopause therapy (HRT) in post-menopausal women
increases the coronary artery risk, epidemiological studies (protection in pre-menopaused …
increases the coronary artery risk, epidemiological studies (protection in pre-menopaused …
Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells
LC Zacharia, EK Jackson, DG Gillespie, RK Dubey - Hypertension, 2001 - Am Heart Assoc
Estradiol may be cardioprotective; however, the mechanisms involved remain unclear.
Recent findings that estradiol attenuates neointima formation in estrogen receptor knockout …
Recent findings that estradiol attenuates neointima formation in estrogen receptor knockout …
Mechanisms whereby oestrogens influence arterial health
JC Stevenson - European Journal of Obstetrics & Gynecology and …, 1996 - Elsevier
Coronary heart disease (CHD) is uncommon in premenopausal women compared with men
of similar age, but its incidence increases after the menopause to reach that of men. There is …
of similar age, but its incidence increases after the menopause to reach that of men. There is …
Estrogen receptors and endothelium
JF Arnal, C Fontaine, A Billon-Galés… - … and Vascular Biology, 2010 - Am Heart Assoc
Estrogens, and in particular 17β-estradiol (E2), play a pivotal role in sexual development
and reproduction and are also implicated in a large number of physiological processes …
and reproduction and are also implicated in a large number of physiological processes …