Estrogen receptors and endothelium

JF Arnal, C Fontaine, A Billon-Galés… - … and Vascular Biology, 2010 - Am Heart Assoc
Estrogens, and in particular 17β-estradiol (E2), play a pivotal role in sexual development
and reproduction and are also implicated in a large number of physiological processes …

Timing of the vascular actions of estrogens in experimental and human studies: why protective early, and not when delayed?

F Lenfant, F Trémollières, P Gourdy, JF Arnal - Maturitas, 2011 - Elsevier
Estrogens, and in particular 17β-estradiol (E2), play a pivotal role in sexual development
and reproduction and are also implicated in a large number of physiological processes …

[HTML][HTML] Cardiovascular system and estrogen in menopause

AAF Carbonel, RS Simões, MJBC Girão… - Revista da Associação …, 2020 - SciELO Brasil
Women are known to have a lower incidence of cardiovascular disease than men of the
same age, but this benefit disappears after menopause. Thus the risk of cardiovascular …

The effects of oestrogens and their receptors on cardiometabolic health

E Morselli, RS Santos, A Criollo, MD Nelson… - Nature Reviews …, 2017 - nature.com
Cardiovascular disease (CVD) is one of the leading causes of mortality in developed
countries. The incidence of CVD is sexually dimorphic, and research has focused on the …

Oestrogen and the cardiovascular system: the good, the bad and the puzzling

GA Gray, I Sharif, DJ Webb, JR Seckl - Trends in pharmacological sciences, 2001 - cell.com
The concept that oestrogen replacement therapy is cardioprotective has been challenged
recently by the negative results of randomized clinical trials in coronary heart disease. These …

Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors

MR Bowling, D Xing, A Kapadia, YF Chen… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—17β-Estradiol (E2) offers cardiovascular protection in young female animals and
postmenopausal women. In contrast, randomized trials of menopausal hormones performed …

Endothelial biology of estrogen and cardiovascular disease

K Chambliss, C Mineo, PW Shaul - Endocrinology, 2023 - academic.oup.com
Although hormone therapy (HT) with estrogen is not recommended as a means of providing
prevention from cardiovascular disease (CVD), the therapeutic use of estrogen for other …

Regulation of endothelial nitric oxide synthase and high-density lipoprotein quality by estradiol in cardiovascular pathology

KE Kypreos, S Zafirovic… - Journal of …, 2014 - journals.sagepub.com
Estrogens have been recognized, in the last 3 decades, as important hormones in direct and
indirect modulation of vascular health. In addition to their direct benefit on cardiovascular …

17β-Estradiol, its metabolites, and progesterone inhibit cardiac fibroblast growth

RK Dubey, DG Gillespie, EK Jackson, PJ Keller - Hypertension, 1998 - Am Heart Assoc
Postmenopausal women (PMW) have increased incidence of cardiovascular disease, and
estrogen substitution therapy has been shown to have cardioprotective effects. Since …

Oestrogens and the heart.

GM Rosano, G Panina - Therapie, 1999 - europepmc.org
The incidence of cardiovascular disease is lower in women before the menopause
compared with men, while menopausal women have an incidence of coronary disease …