Background Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic
inflammation of the joints that affects approximately 1% of the population worldwide. The …

Introduction Rheumatoid arthritis (RA) is a complex multifactorial chronic disease. The
importance of human leukocyte antigen as a major genetic risk factor for RA was studied …

Simple Summary The focus of the genetic studies on rheumatoid arthritis has been on
Europeans or European-derived populations, with limited information available on other …

In this study, we sought to investigate the genetic influence of two HLA‐G 3′‐untranslated
region (3′‐UTR) polymorphisms–14 bp (rs66554220) and+ 3142C> G (rs1063320) and …

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease with an increased
prevalence in Mexico. Although its etiology is unknown, its development can be influenced …

Background: Previous studies have reported an interaction between ever cigarette smoking
and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE) …

OBJECTIVES: To estimate the common effect size of HLA-DRB1 alleles on rheumatoid
arthritis (RA) susceptibility across Latin America populations through a meta-analysis …

The HLA-DRB1 alleles encoding an amino acid sequence (QKRAA/QRRAA/RRRAA) at
position 70 74 of the third hypervariable region of the β1 chain of the HLA-DRB1 gene …

OBJECTIVE: To investigate the association of predisposing and protective HLA-DRB1
alleles with rheumatoid arthritis (RA) and its clinical markers in a Taiwanese population …

Background Earlier studies have demonstrated that smoking and genetic risk factors interact
in providing an increased risk of rheumatoid arthritis (RA). Less is known on how smoking …