Interaction between smoking and HLA-DRB1* 04 gene is associated with a high cardiovascular risk in Brazilian Amazon patients with rheumatoid arthritis
NO Boechat, MM Ogusku, AL Boechat, A Sadahiro - 2012 - journals.plos.org
Background Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic
inflammation of the joints that affects approximately 1% of the population worldwide. The …
inflammation of the joints that affects approximately 1% of the population worldwide. The …
HLA-DRB1 allele association with rheumatoid arthritis susceptibility and severity in Syria
Introduction Rheumatoid arthritis (RA) is a complex multifactorial chronic disease. The
importance of human leukocyte antigen as a major genetic risk factor for RA was studied …
importance of human leukocyte antigen as a major genetic risk factor for RA was studied …
HLA-DRB1*07:01 and *08:02 Alleles Confer a Protective Effect Against ACPA-Positive Rheumatoid Arthritis in a Latin American Admixed Population
Simple Summary The focus of the genetic studies on rheumatoid arthritis has been on
Europeans or European-derived populations, with limited information available on other …
Europeans or European-derived populations, with limited information available on other …
HLA‐G+ 3142 polymorphism as a susceptibility marker in two rheumatoid arthritis populations in Brazil
TD Veit, CPS De Lima, LC Cavalheiro… - Tissue …, 2014 - Wiley Online Library
In this study, we sought to investigate the genetic influence of two HLA‐G 3′‐untranslated
region (3′‐UTR) polymorphisms–14 bp (rs66554220) and+ 3142C> G (rs1063320) and …
region (3′‐UTR) polymorphisms–14 bp (rs66554220) and+ 3142C> G (rs1063320) and …
Role of HLA-DRB1* 04 in the susceptibility and HLA-DRB1* 08 in the protection for development of rheumatoid arthritis in a population of Southern Mexico: brief report
J Sepúlveda-Delgado, A Rizo-Pinto… - Clinical …, 2020 - Springer
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease with an increased
prevalence in Mexico. Although its etiology is unknown, its development can be influenced …
prevalence in Mexico. Although its etiology is unknown, its development can be influenced …
Gene–environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis
EW Karlson, SC Chang, J Cui, LB Chibnik… - Annals of the …, 2010 - ard.bmj.com
Background: Previous studies have reported an interaction between ever cigarette smoking
and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE) …
and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE) …
Meta-analysis of HLA-DRB1 polymorphism in Latin American patients with rheumatoid arthritis
AM Delgado-Vega, JM Anaya - Autoimmunity reviews, 2007 - Elsevier
OBJECTIVES: To estimate the common effect size of HLA-DRB1 alleles on rheumatoid
arthritis (RA) susceptibility across Latin America populations through a meta-analysis …
arthritis (RA) susceptibility across Latin America populations through a meta-analysis …
Study of the frequency of HLA-DRB1 alleles in Brazilian patients with rheumatoid arthritis
MJG Usnayo, LEC Andrade, RT Alarcon… - Revista Brasileira de …, 2011 - SciELO Brasil
The HLA-DRB1 alleles encoding an amino acid sequence (QKRAA/QRRAA/RRRAA) at
position 70 74 of the third hypervariable region of the β1 chain of the HLA-DRB1 gene …
position 70 74 of the third hypervariable region of the β1 chain of the HLA-DRB1 gene …
Influence of HLA-DRB1 genes and the shared epitope on genetic susceptibility to rheumatoid arthritis in Taiwanese.
SC Liu, TY Chang, YJ Lee, CC Chu, M Lin… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To investigate the association of predisposing and protective HLA-DRB1
alleles with rheumatoid arthritis (RA) and its clinical markers in a Taiwanese population …
alleles with rheumatoid arthritis (RA) and its clinical markers in a Taiwanese population …
Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke
H Källberg, B Ding, L Padyukov, C Bengtsson… - Annals of the …, 2011 - ard.bmj.com
Background Earlier studies have demonstrated that smoking and genetic risk factors interact
in providing an increased risk of rheumatoid arthritis (RA). Less is known on how smoking …
in providing an increased risk of rheumatoid arthritis (RA). Less is known on how smoking …
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