While it is well known that production of new neurons from neural stem/progenitor cells
(NSC) in the dentate gyrus (DG) diminishes greatly by middle age, the phases and …

To investigate whether dramatically waned dentate neurogenesis during aging is linked to
diminution in neural stem/progenitor cell (NSC) number, we counted cells immunopositive …

The identification of neurogenesis in the dentate gyrus of adult mammals has sparked much
interest in a functional role for these new neurons in hippocampal‐dependent cognition. The …

Hippocampal neurogenesis declines steadily over the first year of life in the rodent, but the
process persists into senescence despite a dramatic drop in the number of neurons it …

Addition of new granule cells to the dentate gyrus (DG) from stem or progenitor cells
declines considerably during ageing. However, potential age‐related alterations in …

Age‐related decrements in hippocampal neurogenesis have been suggested as a basis for
learning impairment during aging. In the current study, a rodent model of age‐related …

Strong age-related declines in conjunction with comparatively easy experimental
manipulations of adult hippocampal neurogenesis have generated considerable public and …

The generation of new neurons in the adult mammalian brain is well-established for the
hippocampal dentate gyrus (DG). However, the role of neurogenesis in hippocampal …

Hippocampal neurogenesis continuously declines in the aging brain but only little is known
about age-related alterations in the subgranular zone (SGZ) of the dentate gyrus which …

In the rodent brain, diverse functions are topographically distributed within the hippocampus.
For instance, the dorsal (septal) hippocampus is involved in spatial memory, whereas the …