Two series of 2-substituted aryl, heteroaryl and alkyl, 4-substituted aryl 1, 3-oxazole (2a-k)
and thiazole (4a-k) molecular scaffolds containing divalent bioisosteres, viz., oxygen and …

The bioisosteres of 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles are well-known
pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1, 3, 4 …

The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-
known heterocycles, being a common and essential feature of a variety of natural products …

In the present investigation, a series of 2 (4-pyridyl)-5 [(aryl/heteroarylamino)-1-oxoethyl] thio-
1, 3, 4-oxadiazole were synthesized using isonicotinohydrazide and substituted …

A new series of bis ((5-aryl-1, 3, 4-oxadiazol-2-yl) thio) alkanes 4–14 have been synthesized
via nucleophilic substitution reaction of dihaloalkanes with respective 1, 3, 4-oxadiazole-2 …

Since the introduction of the first antibiotic (penicillin, 1942) into medical practice, to date,
there has been an ongoing “race” between scientists creating new drugs and pathogenic …

By introducing the pyridinium group into 2, 5-substituted-1, 3, 4-oxadiazole, a series of
pyridinium-tailored 2, 5-substituted-1, 3, 4-oxadiazole thioether/sulfoxide/sulfone derivatives …

In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are
reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti …

Some novel oxazolidinone derivatives with benzotriazole as pendant have been
synthesized and tested for antibacterial activity. Linearly attached benzotriazole derivative …

A novel series of 5-(2-benzylsulfanyl-pyridin-3-yl)-2-(substituted)-sulfanyl-1, 3, 4-
oxadiazoles 6a–j were synthesized from key intermediate 5-(2-benzylsulfanyl-pyridin-3-yl) …