There is a critical need for improving the level of chemistry awareness in systems biology.
The data and information related to modulation of genes and proteins by small molecules …

The increasing availability of data related to genes, proteins and their modulation by small
molecules has provided a vast amount of biological information leading to the emergence of …

The cost of drug development is increasing, and investment returns are decreasing. The
number of drugs approved by FDA is in decline in terms of the number of new molecular …

For many years, the “one target, one drug” paradigm has been the driving force behind
developments in pharmaceutical research. With the recent advances in molecular biology …

Growth in the pharmaceutical market has slowed down–almost to a standstill. One reason is
that governments and other payers are cutting costs in a faltering world economy. But a …

Despite the promises made that genomic sequencing would transform therapy by
introducing a new era of personalized medicine, relatively few tangible breakthroughs have …

Quantitative systems pharmacology (QSP) modeling represents an emerging area of value
to further streamline knowledge integration and to better inform decision making processes …

The first book to focus on comprehensive systems biology as applied to drug discovery and
development Drawing on real-life examples, Systems Biology in Drug Discovery and …

To achieve sensitive and specific mechanism-based prediction of drug toxicity, the tools of
systems pharmacology will be integrated using structured ontological approaches, analytics …

For over a decade, cheminformatics has contributed to a wide array of scientific tasks from
analytical chemistry and biochemistry to pharmacology and drug discovery; and although its …