Significance: Raman spectroscopy has been developed for surgical guidance applications
interrogating live tissue during tumor resection procedures to detect molecular contrast …

Raman systems have tremendous potential as adjunct devices for endoscopes to improve
the identification of early colon cancers. However, the traditional low frequency (LF) …

Stimulated Raman scattering (SRS) microscopy for biomedical analysis can provide a
molecular localization map to infer pathological tissue changes. Compared to spontaneous …

Aims: To test the spectral reproducibility of earlier findings under ex vivo conditions and to
record good quality in vivo spectra in clinically implementable time in finger print region …

Background Despite significant advances in treatment modalities, the 5 year survival rate in
oral and oropharyngeal squamous cell carcinoma (SCC) is less than 60%. Clinical …

Purpose Raman spectroscopy is a promising cancer detection technique for surgical
guidance applications. It can provide quantitative information relating to global tissue …

This study aims to evaluate the utility of a home-made surface-enhanced Raman
spectroscopy (SERS) system for detection of nasopharyngeal cancer (NPC). A Raman …

Raman spectroscopy is a noninvasive, nondestructive analytical method capable of
determining the biochemical constituents based on molecular vibrations. It does not require …

We report on the development of a novel, to the best of our knowledge, coaxial double-clad-
fiber (DCF) and graded-index (GRIN) fiberoptic Raman probe for enhancing epithelial tissue …

Raman spectroscopy is a vibrational spectroscopic technique capable of nondestructively
probing endogenous biomolecules and their changes associated with dysplastic …