[HTML][HTML] FGF23 induces left ventricular hypertrophy
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease
M Leifheit-Nestler, R große Siemer… - Nephrology Dialysis …, 2016 - academic.oup.com
Background In chronic kidney disease (CKD), serum concentrations of fibroblast growth
factor 23 (FGF23) increase progressively as glomerular filtration rate declines, while renal …
factor 23 (FGF23) increase progressively as glomerular filtration rate declines, while renal …
FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice
There is controversy regarding whether excess FGF23 causes left ventricular hypertrophy
(LVH) directly through activation of fibroblast growth factor receptor 4 (FGFR4) in …
(LVH) directly through activation of fibroblast growth factor receptor 4 (FGFR4) in …
Fibroblast growth factor–23 and cardiac structure and function
Background Fibroblast growth factor–23 (FGF‐23) is a phosphaturic factor previously
associated with left ventricular hypertrophy and systolic dysfunction among individuals with …
associated with left ventricular hypertrophy and systolic dysfunction among individuals with …
[HTML][HTML] Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy
Chronic kidney disease (CKD) is a worldwide public health threat that increases risk of
death due to cardiovascular complications, including left ventricular hypertrophy (LVH) …
death due to cardiovascular complications, including left ventricular hypertrophy (LVH) …
[HTML][HTML] Paracrine effects of FGF23 on the heart
M Leifheit-Nestler, D Haffner - Frontiers in endocrinology, 2018 - frontiersin.org
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone primarily secreted by
osteocytes to maintain phosphate and mineral homeostasis. In patients with and without …
osteocytes to maintain phosphate and mineral homeostasis. In patients with and without …
Fibroblast growth factor 23, left ventricular mass, and left ventricular hypertrophy in community-dwelling older adults
A Jovanovich, JH Ix, J Gottdiener, K McFann, R Katz… - Atherosclerosis, 2013 - Elsevier
Objectives In chronic kidney disease (CKD), high FGF23 concentrations are associated with
left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of …
left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of …
[HTML][HTML] FGF23/FGFR4-mediated left ventricular hypertrophy is reversible
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac
myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the …
myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the …
FGF23 from bench to bedside
CP Kovesdy, LD Quarles - American Journal of Physiology …, 2016 - journals.physiology.org
There is a strong association between elevated circulating fibroblast growth factor-23
(FGF23) levels and adverse outcomes in patients with chronic kidney disease (CKD) of all …
(FGF23) levels and adverse outcomes in patients with chronic kidney disease (CKD) of all …
[HTML][HTML] Update on fibroblast growth factor 23 in chronic kidney disease
M Wolf - Kidney international, 2012 - Elsevier
Chronic kidney disease (CKD) is a public health epidemic that affects millions of people
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …