Background Tumor-associated macrophages (TAM) play an important role in tumor
microenvironment. Particularly, M2 macrophages contribute to tumor progression …

Growing evidence links tumor progression with chronic inflammatory processes and
dysregulated activity of various immune cells. In this study, we demonstrate that various …

Exosome-mediated intercellular communication is considered to be an effective mode for
malignant cells to transform biological behaviors in stromal cells. However, the mechanisms …

Tumor-associated macrophages (TAMs) play a critical role in the tumor inflammatory
microenvironment and facilitate tumor growth and metastasis. Most types of tumors …

Small membranous secretions from tumor cells, termed exosomes, contribute significantly to
intercellular communication and subsequent reprogramming of the tumor microenvironment …

Tumor-derived exosomes are being recognized as essential mediators of intercellular
communication between cancer and immune cells. It is well established that bone marrow …

Background Exosomes are extracellular vesicles that mediate cellular communication in
health and diseases. Neutrophils could be polarized to a pro-tumor phenotype by tumor. The …

Cancer-associated fibroblasts (CAFs) are an essential component in the tumor
microenvironment and have been reported to contribute to tumor progression through many …

Gastric cancer is one of the leading causes of cancer-related death due to late diagnosis
with high metastatic frequency. In this study, the impact of tumor secreted exosomes on …

Exosomes are emerging as important elements that participate in intercellular
communication and tumor microenvironment modulation, but the exact mechanisms by …